Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DQM55_RS04155 Genome accession   NZ_LS483364
Coordinates   789777..791126 (+) Length   449 a.a.
NCBI ID   WP_002899938.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11086     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 784777..796126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS04120 (NCTC11086_00814) - 784868..785245 (+) 378 WP_002899930.1 carboxymuconolactone decarboxylase family protein -
  DQM55_RS04125 (NCTC11086_00815) - 785332..785682 (-) 351 WP_111675560.1 hypothetical protein -
  DQM55_RS04130 (NCTC11086_00816) - 785791..786450 (-) 660 WP_049547961.1 amino acid ABC transporter permease -
  DQM55_RS04135 (NCTC11086_00817) - 786461..787141 (-) 681 WP_111675561.1 amino acid ABC transporter permease -
  DQM55_RS04140 (NCTC11086_00818) - 787154..787966 (-) 813 WP_111675562.1 transporter substrate-binding domain-containing protein -
  DQM55_RS04145 (NCTC11086_00819) - 787981..788742 (-) 762 WP_111675563.1 amino acid ABC transporter ATP-binding protein -
  DQM55_RS04150 (NCTC11086_00820) micA 789083..789784 (+) 702 WP_002894937.1 response regulator YycF Regulator
  DQM55_RS04155 (NCTC11086_00821) micB 789777..791126 (+) 1350 WP_002899938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM55_RS04160 (NCTC11086_00822) vicX 791136..791936 (+) 801 WP_111675564.1 MBL fold metallo-hydrolase Regulator
  DQM55_RS04165 (NCTC11086_00823) - 792028..792387 (+) 360 WP_002894940.1 DUF454 family protein -
  DQM55_RS04170 (NCTC11086_00824) rnc 792509..793207 (+) 699 WP_111675565.1 ribonuclease III -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50975.86 Da        Isoelectric Point: 4.3896

>NTDB_id=1138666 DQM55_RS04155 WP_002899938.1 789777..791126(+) (micB) [Streptococcus sanguinis strain NCTC11086]
MIEAIKQFVISADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDDI

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1138666 DQM55_RS04155 WP_002899938.1 789777..791126(+) (micB) [Streptococcus sanguinis strain NCTC11086]
ATGATTGAAGCAATTAAACAATTTGTGATTTCTGCGGATTTTGTCTTTGCAATCATTATTATCGGCTTCATTGTAGTTGT
GGCCTTGCTTTTATTGGAAAATCGCCGTGATAACCAAAAGCTTGTACAGCTTAATCAAAAGGTTAAAGATTTGATTGCAG
GGGACTATTCTGAAGTGCTGGATATGCAGGGAAGTCCAGAAATCACAGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGACTGACACATGAAAACCTTGAGCAAGAAACAAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGCGT
GCTTGCGACCAACCGCCGGGGACAGATTATCACTATCAACGATATGGCAACTAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGAGGGACCTGATTACCAATGTTCCTGAG
CTGACGATAGATTCTCAGGATGAAAATGGTGAGTACTTGAGCTTGCGGGTTCGCTTTGCCTTGGTAAGGCGGGAGTCGGG
CTTCATTTCTGGTTTGGTAGCTGTCTTGCATGATACGACCGAGCAGGACAAGGAAGAGCGGGAGCGTCGCCTCTTTGTCT
CCAACGTCAGCCATGAGTTGCGGACTCCGCTGACCAGTGTTAAGTCCTATCTGGAAGCCCTGGATGAGGGAGCCTTGTCT
GAGCCAGTAGCACCGGACTTTGTCAAGGTATCGCTCAATGAAACCAACCGCATGATGCGGATGGTGACGGACTTGCTCAG
CTTGTCACGCATTGACAATGAGACCAGTCATCTAGAAGTGGAGCTGACGAATTTCACGGCTTTTATTACCTTTATCCTCA
ATCGCTTTGACAAGATAAAAAACCAAGACGAGACTAAGAAATATGAGATTATCCGTGATTATCCGATAACACCGATCTGG
GTGGAGATTGATACAGATAAGCTGACCCAGGTCATTGATAATATCATGAACAATGCCATCAAGTATTCACCAGATGGTGG
AACCATTACTGTTTCCATCAAGACAACGGATGAGCAGTTGATTCTCTCAATTGCGGATGAAGGTCTGGGGATTCCCAAGC
AGGACCTGCCTAAGATTTTTGATCGCTTTTATCGAGTGGACAAGGCACGCAGCCGCGCACAGGGCGGAACGGGTCTGGGG
TTGGCCATTGCTAAGGAAATTATCAAGCAGCATCAGGGCTTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTCTTGCCTTATGAGAATGATGGCGTCCGGGATGACGACTGGGATAATGAAGATGATATATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

97.773

0.768
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment