Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQM53_RS02200 Genome accession   NZ_LS483361
Coordinates   407439..408125 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 402439..413125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM53_RS02175 (NCTC6179_00441) ktrB 402549..403925 (-) 1377 WP_111715242.1 potassium uptake transporter channel subunit KtrB -
  DQM53_RS02180 (NCTC6179_00442) rsmG 404009..404722 (-) 714 WP_111715245.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQM53_RS02185 (NCTC6179_00443) - 404875..405432 (+) 558 WP_111715248.1 LemA family protein -
  DQM53_RS02190 (NCTC6179_00444) htpX 405477..406370 (+) 894 WP_111715251.1 zinc metalloprotease HtpX -
  DQM53_RS02195 (NCTC6179_00445) - 406636..407169 (+) 534 WP_111715253.1 DUF177 domain-containing protein -
  DQM53_RS02200 (NCTC6179_00446) covR 407439..408125 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  DQM53_RS02205 (NCTC6179_00447) - 408131..409630 (+) 1500 WP_111715255.1 HAMP domain-containing histidine kinase -
  DQM53_RS02210 (NCTC6179_00448) - 409854..410987 (+) 1134 WP_111714946.1 ISAs1 family transposase -
  DQM53_RS02220 (NCTC6179_00449) nrdR 411161..411655 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  DQM53_RS02225 (NCTC6179_00450) - 411639..412817 (+) 1179 WP_111715260.1 DnaD domain protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1138513 DQM53_RS02200 WP_003049736.1 407439..408125(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1138513 DQM53_RS02200 WP_003049736.1 407439..408125(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGAATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment