Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQM70_RS04715 Genome accession   NZ_LS483358
Coordinates   1028593..1029795 (-) Length   400 a.a.
NCBI ID   WP_005601207.1    Uniprot ID   Q7BI81
Organism   Actinobacillus pleuropneumoniae strain NCTC11384     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1023593..1034795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM70_RS04690 (NCTC11384_00959) lptE 1025393..1025887 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  DQM70_RS04695 (NCTC11384_00960) holA 1025996..1027021 (+) 1026 WP_005601200.1 DNA polymerase III subunit delta -
  DQM70_RS04700 (NCTC11384_00961) yacG 1027098..1027286 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  DQM70_RS04705 (NCTC11384_00962) coaE 1027268..1027906 (-) 639 WP_005601202.1 dephospho-CoA kinase -
  DQM70_RS04710 (NCTC11384_00963) - 1027928..1028566 (-) 639 WP_005604550.1 prepilin peptidase -
  DQM70_RS04715 (NCTC11384_00964) pilC 1028593..1029795 (-) 1203 WP_005601207.1 type II secretion system F family protein Machinery gene
  DQM70_RS04720 (NCTC11384_00965) pilB 1029779..1031173 (-) 1395 WP_005597396.1 GspE/PulE family protein Machinery gene
  DQM70_RS04725 (NCTC11384_00966) pilA 1031191..1031637 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQM70_RS04730 (NCTC11384_00967) radA 1031819..1033198 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  DQM70_RS04735 (NCTC11384_00968) - 1033242..1033475 (-) 234 WP_005597399.1 YgjV family protein -
  DQM70_RS04740 (NCTC11384_00969) folA 1033602..1034090 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45588.09 Da        Isoelectric Point: 10.3239

>NTDB_id=1138363 DQM70_RS04715 WP_005601207.1 1028593..1029795(-) (pilC) [Actinobacillus pleuropneumoniae strain NCTC11384]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRHQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSHFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLAAQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=1138363 DQM70_RS04715 WP_005601207.1 1028593..1029795(-) (pilC) [Actinobacillus pleuropneumoniae strain NCTC11384]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCCATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCACTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTGCACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7BI81

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

50.126

99.25

0.498
  pilC Haemophilus influenzae Rd KW20

39.5

100

0.395
  pilC Haemophilus influenzae 86-028NP

38.5

100

0.385

Multiple sequence alignment