Detailed information NTG1138117

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQL39_RS07625
• Genome accession: NZ_LS483353
• Coordinates: 1485912..1486346 (-)
• Length: 144 a.a.
• NCBI ID: WP_002986542.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC4001
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1480912..1491346

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL39_RS07600 (NCTC4001_01510)	proC	1481948..1482718 (+)	771	WP_038433086.1	pyrroline-5-carboxylate reductase	-
DQL39_RS07605	-	1482801..1483109 (-)	309	WP_030126458.1	hypothetical protein	-
DQL39_RS07610 (NCTC4001_01511)	-	1483296..1484492 (-)	1197	WP_038433085.1	acetate kinase	-
DQL39_RS07615 (NCTC4001_01512)	comYH	1484551..1485504 (-)	954	WP_038433084.1	class I SAM-dependent methyltransferase	Machinery gene
DQL39_RS07620 (NCTC4001_01513)	comGG	1485602..1485928 (-)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
DQL39_RS07625 (NCTC4001_01514)	comYF	1485912..1486346 (-)	435	WP_002986542.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL39_RS07630 (NCTC4001_01515)	comGE	1486339..1486623 (-)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
DQL39_RS07635 (NCTC4001_01516)	comGD	1486580..1487008 (-)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQL39_RS07640 (NCTC4001_01517)	comYC	1486983..1487309 (-)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL39_RS07645 (NCTC4001_01518)	comYB	1487311..1488345 (-)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL39_RS07650 (NCTC4001_01519)	comYA	1488281..1489219 (-)	939	WP_032460336.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL39_RS07655 (NCTC4001_01520)	-	1489312..1489677 (-)	366	WP_002986560.1	DUF1033 family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16573.20 Da
• Isoelectric Point: 10.3584

>NTDB_id=1138117 DQL39_RS07625 WP_002986542.1 1485912..1486346(-) (comYF) [Streptococcus pyogenes strain NCTC4001]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1138117 DQL39_RS07625 WP_002986542.1 1485912..1486346(-) (comYF) [Streptococcus pyogenes strain NCTC4001]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396