Detailed information NTG1137819

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQM48_RS02925
• Genome accession: NZ_LS483348
• Coordinates: 537530..539764 (+)
• Length: 744 a.a.
• NCBI ID: WP_043894997.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC8738
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 532530..544764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM48_RS02900 (NCTC8738_00594)	-	533272..534849 (+)	1578	WP_020916419.1	DEAD/DEAH box helicase	-
DQM48_RS02905 (NCTC8738_00595)	-	534890..535165 (-)	276	WP_020916420.1	GIY-YIG nuclease family protein	-
DQM48_RS02910 (NCTC8738_00596)	-	535140..535901 (-)	762	WP_020916421.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
DQM48_RS02915 (NCTC8738_00597)	-	536017..536763 (+)	747	WP_043894996.1	lysophospholipid acyltransferase family protein	-
DQM48_RS02920 (NCTC8738_00598)	-	536860..537540 (+)	681	WP_020916423.1	helix-hairpin-helix domain-containing protein	-
DQM48_RS02925 (NCTC8738_00599)	comEC/celB	537530..539764 (+)	2235	WP_043894997.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQM48_RS02930 (NCTC8738_00600)	holA	539829..540866 (+)	1038	WP_020916425.1	DNA polymerase III subunit delta	-
DQM48_RS02935 (NCTC8738_00601)	-	540961..541572 (+)	612	WP_020916426.1	superoxide dismutase	-
DQM48_RS02940 (NCTC8738_00602)	-	541674..542399 (+)	726	WP_043894998.1	YebC/PmpR family DNA-binding transcriptional regulator	-
DQM48_RS02945 (NCTC8738_00603)	queA	542450..543478 (-)	1029	WP_020916428.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
DQM48_RS02950 (NCTC8738_00604)	-	543642..544148 (+)	507	WP_058833169.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84241.65 Da
• Isoelectric Point: 8.6678

>NTDB_id=1137819 DQM48_RS02925 WP_043894997.1 537530..539764(+) (comEC/celB) [Streptococcus lutetiensis strain NCTC8738]
MLIKHFPVKPIQLAFLLILLYYFCFSKGIGCLMFLLLALLFLWQQYGWKAWYQVSLCLAFFAIFFLTKANQTEQAYQAAP
TQLAKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYILKSEKEQEFFKNLNQTMLLSGQVDLEEATPQRNFGGFDYRTYLK
HEGIYRIANLSSITEIRQQSSLSFFERLHELRRQAIVSIQRNFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFA
LSGMQVGFFVALFRFIILRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLAFTLMTLFILMP
NFLLTTGGILSFTYAFILSFIDFDELSHYQKILTECFAISLGSLPVLLYFFSVFQPLSLLLTAIFSLAFDTLILPVLTFV
FLLSPLVKITALNPFFVFLETIIKFSKSLIGTPLVFGRPSLGILLLLLLIIGLLYDCYRHKKVAIFLFSIIALLFFQIKH
PLENEVTVVDIGQGDSILVRDVKGQTLLIDVGGKVRFSEKKSWQKRLADSNAERTLIPYLKSRGIGKIDQLVLTHTDTDH
MGDMLEVAKELKIGQVLVSPGSLTKPDFVVKLRQMKTPVHAVSAGDNLPIMGSHLQVLYPNAVGDGGNNDSVVLYGNLLG
KNFLFTGDLEEEGEEQMMATYPNLPVDVLKAGHHGSKGSSSPEFLDHISPQMALISAGQNNRYKHPHQETLDRFQNQNMT
IYRTDQQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=1137819 DQM48_RS02925 WP_043894997.1 537530..539764(+) (comEC/celB) [Streptococcus lutetiensis strain NCTC8738]
CTGTTGATTAAGCATTTCCCTGTCAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAA
AGGGATTGGGTGTTTGATGTTTCTCTTGCTAGCTTTGCTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTATCAGG
TTTCACTGTGTTTGGCTTTTTTTGCGATATTTTTCCTGACTAAGGCTAATCAGACAGAACAGGCTTATCAAGCGGCGCCA
ACTCAGCTAGCAAAAATACAGATGATTCCAGATACGATTTCGGTTAATGGTGATTTGTTATCTTTTCGAGGGAAGGAGGC
TGGGCAGACTTACCAAGTTTTTTATATCTTGAAGTCAGAAAAAGAGCAGGAATTTTTTAAAAATCTTAATCAAACAATGC
TTTTATCAGGGCAGGTGGATCTAGAAGAGGCAACGCCACAACGGAATTTTGGTGGTTTTGATTACCGCACTTACCTTAAA
CATGAAGGCATTTATCGGATTGCTAATCTTTCTTCGATTACTGAAATAAGACAGCAGAGCTCTTTAAGTTTTTTTGAACG
ACTACATGAACTTAGAAGACAGGCGATTGTCAGTATTCAAAGGAATTTTCCTGCTCCCATGCAACATTACATGACTGGCC
TTTTGTTTGGATATTTGGATAAGTCTTTTGATGAGATGAGTGATGTTTATACTAGTTTAGGGATTATTCATCTTTTTGCT
CTGTCTGGTATGCAGGTAGGCTTTTTTGTGGCACTTTTTCGTTTTATTATTTTACGTCTTGGGTTACGGCGAGATTATGT
GGATATACTGCAAATCCCGTTTTCACTTGTATATGCTGGCTTGACAGGCTTTTCGGTATCAGTGATTCGTAGTTTAATTC
AGTCTGCCTTTGCAAATCTTGGTATTAAAAAATTAGATAATCTTGCCTTTACTTTAATGACCCTTTTTATTTTGATGCCA
AATTTCCTGCTAACAACAGGAGGAATTCTTTCTTTTACCTACGCTTTCATCCTGAGTTTTATTGATTTTGATGAGCTTAG
TCATTATCAAAAAATCCTTACAGAATGTTTTGCGATTTCGCTGGGAAGTTTACCGGTTTTGCTATATTTCTTCTCAGTAT
TTCAACCTTTGTCGCTGCTTTTAACAGCTATTTTTTCACTAGCTTTTGATACGCTTATCTTACCTGTTTTGACCTTTGTT
TTTCTTTTATCACCTCTGGTTAAAATTACCGCGTTAAATCCATTTTTTGTTTTTTTGGAAACTATCATCAAATTTAGTAA
GTCGCTGATTGGCACACCACTTGTTTTTGGCAGACCAAGTCTAGGAATTTTGTTGCTATTACTTTTAATAATAGGACTTC
TCTATGACTGTTATCGACACAAAAAAGTGGCCATTTTCCTTTTTAGCATAATAGCTTTGCTATTTTTCCAAATCAAGCAT
CCGCTCGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGCATTTTGGTGCGAGATGTAAAGGGGCAGACGCT
GTTAATTGATGTCGGAGGAAAAGTGAGGTTTAGTGAGAAAAAATCGTGGCAAAAGCGCTTAGCTGATAGCAATGCTGAGC
GGACATTGATTCCTTATCTGAAAAGTCGAGGAATTGGTAAAATTGATCAGTTAGTTTTGACGCACACGGATACCGACCAT
ATGGGCGATATGCTGGAAGTCGCAAAAGAGCTGAAAATTGGTCAAGTCCTGGTGAGTCCAGGAAGTCTCACAAAGCCAGA
TTTTGTGGTTAAACTTCGACAAATGAAGACGCCAGTTCACGCAGTTTCTGCAGGAGATAACTTGCCAATTATGGGAAGTC
ACTTGCAGGTGCTTTATCCGAATGCTGTTGGTGATGGTGGAAATAATGATTCTGTGGTGCTTTATGGTAATCTTCTGGGT
AAGAATTTCTTGTTTACTGGAGACTTGGAAGAAGAGGGCGAAGAGCAGATGATGGCAACTTATCCCAATCTGCCAGTCGA
TGTCTTAAAAGCAGGACATCACGGTTCAAAAGGGTCATCGAGCCCAGAATTTCTAGATCACATTTCACCACAAATGGCTT
TGATTTCCGCAGGGCAAAATAACCGTTACAAACACCCTCACCAAGAAACACTTGATCGTTTTCAAAATCAAAATATGACC
ATTTACCGCACAGACCAACAAGGTGCTATCCGTTTTAGAGGATTAAACCACTGGAAAATTGAAACGGTGAGGTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-175)

• Competence protein (Competence) (214-455)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-686)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	50.809	99.731	0.507
comEC/celB	Streptococcus mitis NCTC 12261	50.809	99.731	0.507
comEC/celB	Streptococcus pneumoniae TIGR4	49.933	99.866	0.499
comEC/celB	Streptococcus pneumoniae Rx1	49.394	99.866	0.493
comEC/celB	Streptococcus pneumoniae D39	49.394	99.866	0.493
comEC/celB	Streptococcus pneumoniae R6	49.394	99.866	0.493
comEC	Lactococcus lactis subsp. cremoris KW2	47.46	100	0.477