Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DQM73_RS08095 Genome accession   NZ_LS483346
Coordinates   1642176..1643525 (-) Length   449 a.a.
NCBI ID   WP_002899938.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11085     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1637176..1648525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS08075 (NCTC11085_01584) rnc 1638868..1639566 (-) 699 WP_002899941.1 ribonuclease III -
  DQM73_RS08080 (NCTC11085_01585) - 1639689..1640048 (-) 360 WP_032908117.1 YbaN family protein -
  DQM73_RS08085 (NCTC11085_01586) - 1640152..1641093 (-) 942 WP_002923960.1 hypothetical protein -
  DQM73_RS08090 (NCTC11085_01587) vicX 1641366..1642166 (-) 801 WP_002923959.1 MBL fold metallo-hydrolase Regulator
  DQM73_RS08095 (NCTC11085_01588) micB 1642176..1643525 (-) 1350 WP_002899938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM73_RS08100 (NCTC11085_01589) micA 1643518..1644219 (-) 702 WP_002894937.1 response regulator YycF Regulator
  DQM73_RS08105 (NCTC11085_01590) - 1644559..1645320 (+) 762 WP_002920730.1 amino acid ABC transporter ATP-binding protein -
  DQM73_RS08110 (NCTC11085_01591) - 1645335..1646147 (+) 813 WP_002923957.1 transporter substrate-binding domain-containing protein -
  DQM73_RS08115 (NCTC11085_01592) - 1646160..1646840 (+) 681 WP_002906090.1 amino acid ABC transporter permease -
  DQM73_RS08120 (NCTC11085_01593) - 1646851..1647510 (+) 660 WP_002923955.1 amino acid ABC transporter permease -
  DQM73_RS08125 (NCTC11085_01594) - 1647619..1648017 (+) 399 WP_002923953.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50975.86 Da        Isoelectric Point: 4.3896

>NTDB_id=1137708 DQM73_RS08095 WP_002899938.1 1642176..1643525(-) (micB) [Streptococcus sanguinis strain NCTC11085]
MIEAIKQFVISADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDDI

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1137708 DQM73_RS08095 WP_002899938.1 1642176..1643525(-) (micB) [Streptococcus sanguinis strain NCTC11085]
ATGATTGAAGCAATTAAACAATTTGTGATTTCTGCGGATTTTGTCTTTGCAATCATTATTATCGGCTTCATTGTAGTTGT
TGCCTTGCTTTTATTGGAAAATCGCCGCGATAACCAAAAGCTTGTACAGCTTAATCAGAAGGTTAAAGATTTGATTGCAG
GGGACTATTCTGAAGTGCTGGACATGCAGGGAAGTCCAGAAATCACAGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGACTGACACATGAAAACCTTGAGCAAGAAACAAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGCGT
GCTCGCGACTAACCGCCGGGGGCAGATTATCACTATCAACGATATGGCAACCAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGCGCGACTTGATTACCAATGTTCCTGAG
CTGACGATTGATTCTCAGGATGAAAATGGTGAGTATTTGAGCTTGCGGGTTCGCTTTGCCTTGGTAAGGCGGGAGTCGGG
CTTCATTTCTGGTTTGGTGGCTGTCTTGCACGACACGACAGAGCAGGACAAGGAAGAGCGGGAGCGTCGCCTCTTTGTCT
CCAACGTCAGCCATGAGTTGCGGACTCCGCTGACCAGTGTTAAGTCCTATCTGGAAGCCTTGGATGAGGGAGCCTTGTCT
GAGCCAGTAGCGCCGGACTTTGTCAAGGTATCACTCAATGAAACCAACCGCATGATGCGGATGGTGACGGACCTACTTAG
TCTGTCTCGTATTGATAATGAGACCAGTCATCTGGAAGTGGAGCTGACGAATTTCACGGCCTTTATCACCTTTATCCTCA
ATCGCTTTGACAAGATAAAAAATCAAGACGAAACCAAGAAATATGAGATTATCCGTGATTATCCGATAACACCGATTTGG
GTAGAGATTGATACAGATAAGCTGACCCAGGTGATTGATAATATCATGAACAATGCCATCAAGTATTCGCCAGATGGTGG
AACCATTACTGTTTCCATCAAGACAACTGATGAGCAGTTGATTCTCTCGATTGCGGATGAAGGTCTGGGGATTCCCAAGC
AGGACCTGCCTAAGATTTTTGACCGCTTTTATCGAGTGGACAAGGCACGCAGCCGTGCACAGGGTGGAACGGGTCTAGGG
CTGGCTATTGCCAAGGAAATTATCAAGCAGCATCAGGGCTTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTCTTGCCTTATGAGAATGATGGTGTTCGGGATGACGACTGGGATAATGAAGACGATATATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

97.773

0.768
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment