Detailed information NTG1137692

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: DQM73_RS03250
• Genome accession: NZ_LS483346
• Coordinates: 627461..628123 (-)
• Length: 220 a.a.
• NCBI ID: WP_002925573.1
• Uniprot ID: A0A2X3VKV0
• Organism: Streptococcus sanguinis strain NCTC11085
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 622461..633123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM73_RS03220 (NCTC11085_00628)	-	622591..623154 (+)	564	WP_002925580.1	aminodeoxychorismate/anthranilate synthase component II	-
DQM73_RS03225 (NCTC11085_00629)	trpD	623165..624169 (+)	1005	WP_002925579.1	anthranilate phosphoribosyltransferase	-
DQM73_RS03230 (NCTC11085_00630)	trpC	624166..624933 (+)	768	WP_002925578.1	indole-3-glycerol phosphate synthase TrpC	-
DQM73_RS03235 (NCTC11085_00631)	-	624920..625507 (+)	588	WP_002925577.1	phosphoribosylanthranilate isomerase	-
DQM73_RS03240 (NCTC11085_00632)	trpB	625497..626720 (+)	1224	WP_002925576.1	tryptophan synthase subunit beta	-
DQM73_RS03245 (NCTC11085_00633)	trpA	626713..627492 (+)	780	WP_002925574.1	tryptophan synthase subunit alpha	-
DQM73_RS03250 (NCTC11085_00634)	cclA/cilC	627461..628123 (-)	663	WP_002925573.1	A24 family peptidase	Machinery gene
DQM73_RS03260 (NCTC11085_00635)	-	628290..628805 (+)	516	WP_002898046.1	DNA starvation/stationary phase protection protein	-
DQM73_RS03265 (NCTC11085_00636)	-	628898..629116 (+)	219	WP_002898045.1	YqgQ family protein	-
DQM73_RS03270 (NCTC11085_00637)	-	629118..629498 (+)	381	WP_002904037.1	rhodanese-like domain-containing protein	-
DQM73_RS03275 (NCTC11085_00638)	-	629588..629815 (+)	228	WP_002910330.1	hypothetical protein	-
DQM73_RS03280 (NCTC11085_00639)	-	629890..630615 (-)	726	WP_002925572.1	16S rRNA pseudouridine(516) synthase	-
DQM73_RS03285 (NCTC11085_00640)	typA	630795..632642 (+)	1848	WP_032908219.1	translational GTPase TypA	-
DQM73_RS03290 (NCTC11085_00641)	-	632666..632935 (+)	270	WP_002898040.1	DUF3165 family protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 24649.92 Da
• Isoelectric Point: 8.9310

>NTDB_id=1137692 DQM73_RS03250 WP_002925573.1 627461..628123(-) (cclA/cilC) [Streptococcus sanguinis strain NCTC11085]
MIHLYFFLLGTVFASFLGLVIDRFPERSVISPASHCNACGKRLAPRDLIPIFSQAMNRLRCRFCGDKIPLRYLFFECLLG
GLFLATSLSILSISQLLVVTMGLTLAIYDQREQQYPLMIWLVFQLLLLMTAGVNLLILFFLALGLLAFFYNLRIGAGDFL
FLASCSAIFSLTETLILIQIASFSGLACFCFKKKKDRLAFVPCLLFGAVVIISYKLLLLG

Nucleotide

• Length: 663 bp

>NTDB_id=1137692 DQM73_RS03250 WP_002925573.1 627461..628123(-) (cclA/cilC) [Streptococcus sanguinis strain NCTC11085]
ATGATTCATCTATACTTTTTTCTACTTGGCACTGTCTTTGCTTCATTCCTAGGCTTGGTCATCGACCGCTTCCCAGAGCG
GTCTGTCATCTCTCCCGCTAGTCATTGCAATGCCTGCGGGAAAAGATTAGCACCGCGTGATTTGATTCCTATTTTTTCCC
AAGCCATGAACCGGCTTCGTTGCCGCTTCTGCGGAGACAAGATTCCCTTACGCTATTTATTTTTTGAATGTCTCTTGGGC
GGTCTTTTTCTGGCAACTTCTCTGAGCATTCTTTCCATTAGTCAATTATTGGTAGTCACCATGGGCTTAACCTTAGCTAT
CTACGATCAAAGAGAGCAGCAATACCCTTTGATGATCTGGTTGGTTTTTCAGCTTTTGCTGCTAATGACAGCAGGCGTTA
ATCTTCTCATACTCTTCTTTTTAGCCTTAGGACTTCTAGCCTTCTTTTATAATCTTCGTATTGGAGCTGGTGACTTTCTC
TTTCTGGCGTCTTGCTCAGCCATTTTCAGCCTGACGGAGACTCTCATCCTTATCCAAATCGCTAGTTTCTCTGGCCTCGC
CTGTTTCTGCTTTAAAAAGAAAAAAGACAGGCTAGCATTTGTACCTTGTCTTTTGTTTGGTGCGGTGGTGATTATTTCTT
ATAAGCTGCTGCTTCTTGGATAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

3D structure

• AlphaFold DB: A0A2X3VKV0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	58.904	99.545	0.586
cclA/cilC	Streptococcus mitis SK321	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae Rx1	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae D39	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae R6	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae TIGR4	56.621	99.545	0.564