Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQL21_RS04480 Genome accession   NZ_LS483343
Coordinates   857525..858838 (+) Length   437 a.a.
NCBI ID   WP_018029744.1    Uniprot ID   A0A2X3Y0K3
Organism   Streptococcus ferus strain NCTC12278     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 852525..863838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS04455 (NCTC12278_00881) - 852595..855138 (+) 2544 WP_018029738.1 M1 family metallopeptidase -
  DQL21_RS04460 (NCTC12278_00882) - 855181..855831 (-) 651 WP_018029739.1 hemolysin III family protein -
  DQL21_RS04465 (NCTC12278_00883) - 855828..856268 (-) 441 WP_018029740.1 DUF1836 domain-containing protein -
  DQL21_RS04470 (NCTC12278_00885) - 856543..856812 (+) 270 WP_018029742.1 hypothetical protein -
  DQL21_RS04475 (NCTC12278_00886) ciaR 856861..857532 (+) 672 WP_018029743.1 response regulator transcription factor Regulator
  DQL21_RS04480 (NCTC12278_00887) ciaH 857525..858838 (+) 1314 WP_018029744.1 cell wall metabolism sensor histidine kinase WalK Regulator
  DQL21_RS04485 (NCTC12278_00888) rpsT 858956..859207 (-) 252 WP_026161880.1 30S ribosomal protein S20 -
  DQL21_RS04490 (NCTC12278_00889) coaA 859260..860180 (-) 921 WP_018029746.1 type I pantothenate kinase -
  DQL21_RS04495 (NCTC12278_00890) - 860294..860884 (+) 591 WP_018029747.1 class I SAM-dependent methyltransferase -
  DQL21_RS04500 (NCTC12278_00891) - 860871..862148 (+) 1278 WP_018029748.1 pyrimidine-nucleoside phosphorylase -
  DQL21_RS04505 (NCTC12278_00892) deoC 862164..862826 (+) 663 WP_018029749.1 deoxyribose-phosphate aldolase -
  DQL21_RS04510 (NCTC12278_00893) - 862849..863235 (+) 387 WP_018029750.1 cytidine deaminase -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49602.71 Da        Isoelectric Point: 9.4157

>NTDB_id=1137598 DQL21_RS04480 WP_018029744.1 857525..858838(+) (ciaH) [Streptococcus ferus strain NCTC12278]
MFDKLRRKSKSENTSYFIHFFAVFSGIFLVMTVIILQVMRFGIYSSVDNSLTKTVDNIEEYVNITLSRSVLNSLTGETSS
EPPSDIKPKGQMVANTHLIVYDKDGNALNSVDSFSGLQNLSLNTNNLKKISEQRAKNFSGQEEVYRTITVKVDSSLYTDA
KYATVVVNTTQLEDANDRYVKIIVSVMAVFWLLSVGASVYLAKWSRKPILESYEKQKAFVENASHELRTPLAVLQNRLES
LFRQPDTTILDNSENIASSLDEVRNMRILTTNLLNLARRDDGIKPEIVEIKPQFFKEIFQNYQMIAEENQKNFYYENQLT
KPIRMDKTLLKQLMTILFDNAIKYSDSNGDISMMVEASDKQLLVKVADNGQGISDTDKSKIFDRFYRVDKARTRQKGGFG
LGLSLAKQIVDSLKGSISVKDNQPKGSIFEVRLPLTK

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=1137598 DQL21_RS04480 WP_018029744.1 857525..858838(+) (ciaH) [Streptococcus ferus strain NCTC12278]
ATGTTTGATAAGCTTAGAAGAAAATCAAAGAGCGAGAACACCTCTTATTTTATCCATTTTTTTGCCGTCTTCTCTGGTAT
CTTTTTAGTCATGACGGTGATTATTTTACAAGTCATGCGTTTTGGCATTTATTCATCGGTTGATAATAGTCTCACCAAAA
CAGTAGACAACATTGAAGAATACGTCAATATCACCCTATCTCGATCGGTGCTCAATTCTTTAACTGGAGAGACATCGTCG
GAGCCGCCATCAGATATTAAGCCTAAGGGGCAAATGGTTGCCAACACACACCTTATTGTTTACGATAAAGATGGTAATGC
GCTAAACAGTGTCGATTCTTTTTCCGGGCTGCAGAATCTTTCGTTAAATACTAACAATCTTAAGAAGATCTCGGAACAGC
GGGCAAAGAATTTTTCAGGTCAGGAGGAAGTCTACCGAACCATAACAGTCAAGGTAGACAGCAGTCTCTATACAGATGCG
AAGTATGCAACGGTCGTCGTCAATACAACGCAGTTGGAGGATGCCAATGATCGTTATGTCAAAATCATTGTCAGTGTCAT
GGCTGTTTTCTGGCTCTTATCTGTCGGAGCCAGTGTTTACTTGGCGAAATGGAGCCGTAAACCTATCTTAGAAAGCTATG
AAAAACAAAAGGCATTTGTTGAGAATGCCAGTCATGAGCTAAGGACGCCTTTGGCTGTTTTACAAAACCGTCTGGAAAGC
TTGTTTAGGCAGCCAGATACTACTATTTTGGACAATAGCGAAAACATTGCTTCCAGCTTAGATGAAGTCCGGAATATGCG
TATTTTAACCACTAATCTACTTAATCTAGCTCGAAGAGATGACGGTATCAAGCCTGAAATAGTAGAAATAAAGCCTCAGT
TCTTTAAGGAAATCTTTCAAAATTATCAGATGATTGCCGAGGAAAACCAAAAGAATTTCTATTATGAAAACCAGCTGACT
AAACCCATTAGAATGGATAAAACGTTGCTCAAACAACTAATGACCATCCTCTTTGATAACGCCATTAAGTACAGTGACAG
TAATGGTGATATCAGCATGATGGTAGAGGCCAGTGATAAACAGCTTCTGGTCAAGGTTGCTGACAATGGCCAAGGGATCT
CTGATACAGACAAGTCTAAAATTTTTGATCGCTTTTATCGAGTTGATAAAGCCAGAACACGGCAAAAAGGTGGCTTTGGT
TTAGGGCTTTCCTTAGCCAAGCAGATTGTAGATAGTTTAAAAGGAAGCATCAGTGTTAAGGATAATCAGCCTAAAGGCTC
AATCTTTGAAGTTCGCCTTCCGCTGACCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(217-282)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3Y0K3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

65.589

99.085

0.65
  ciaH Streptococcus pneumoniae Rx1

54.128

99.771

0.54
  ciaH Streptococcus pneumoniae D39

54.128

99.771

0.54
  ciaH Streptococcus pneumoniae R6

54.128

99.771

0.54
  ciaH Streptococcus pneumoniae TIGR4

54.128

99.771

0.54

Multiple sequence alignment