Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQL21_RS01925 Genome accession   NZ_LS483343
Coordinates   354470..355159 (+) Length   229 a.a.
NCBI ID   WP_018030977.1    Uniprot ID   A0A2X3VDK1
Organism   Streptococcus ferus strain NCTC12278     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 349470..360159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS01905 (NCTC12278_00365) - 349611..352220 (-) 2610 WP_018030980.1 FtsX-like permease family protein -
  DQL21_RS01910 (NCTC12278_00366) - 352226..352933 (-) 708 WP_018030979.1 ABC transporter ATP-binding protein -
  DQL21_RS01915 - 353032..353583 (+) 552 Protein_335 TetR/AcrR family transcriptional regulator -
  DQL21_RS01920 - 353602..354144 (+) 543 WP_026161998.1 DUF177 domain-containing protein -
  DQL21_RS01925 (NCTC12278_00368) covR 354470..355159 (+) 690 WP_018030977.1 response regulator transcription factor Regulator
  DQL21_RS01930 (NCTC12278_00369) nrdR 355256..355750 (+) 495 WP_018030976.1 transcriptional regulator NrdR -
  DQL21_RS01935 (NCTC12278_00370) - 355737..356900 (+) 1164 WP_018030975.1 DnaD domain protein -
  DQL21_RS01940 (NCTC12278_00371) dnaI 356901..357806 (+) 906 WP_018030974.1 primosomal protein DnaI -
  DQL21_RS01945 (NCTC12278_00372) der 357817..359127 (+) 1311 WP_018030973.1 ribosome biogenesis GTPase Der -
  DQL21_RS01950 (NCTC12278_00373) - 359265..359891 (+) 627 WP_018030972.1 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26774.77 Da        Isoelectric Point: 4.9944

>NTDB_id=1137579 DQL21_RS01925 WP_018030977.1 354470..355159(+) (covR) [Streptococcus ferus strain NCTC12278]
MTKKILIIEDEKNLARFVSLELQHEGYEVDVEHNGRTGLEKALEKDYDLILLDLMLPEMDGYEVTRRLFLEKTTYLIMMT
ARDSVMDIVAGLDRGADGYIVKPFAIEELLARVRATFRRQDMEKAKRLPRGENTYRDLQLDPQNRAAIRDGETIPLTKRE
FDLLNALLSNINQVMTREDLLEHVWKYEQETETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1137579 DQL21_RS01925 WP_018030977.1 354470..355159(+) (covR) [Streptococcus ferus strain NCTC12278]
ATGACAAAGAAGATTTTGATTATTGAGGATGAAAAGAATCTGGCTCGGTTTGTATCGCTGGAGTTACAACATGAAGGATA
TGAGGTCGATGTGGAGCATAATGGGCGCACAGGTCTCGAAAAAGCATTAGAAAAAGACTATGATTTGATTTTACTGGATT
TAATGTTGCCCGAAATGGACGGCTATGAGGTGACCCGCCGTCTTTTCCTGGAAAAGACAACATACTTAATCATGATGACT
GCCCGTGATTCAGTCATGGATATTGTAGCTGGTCTTGACCGTGGCGCAGATGGTTATATCGTTAAACCCTTTGCTATTGA
AGAGCTTTTAGCCAGAGTTCGTGCGACTTTCCGCCGTCAAGATATGGAAAAAGCCAAACGTCTGCCACGCGGGGAAAATA
CTTACCGTGACCTGCAATTAGACCCGCAGAATCGAGCGGCTATTCGTGACGGGGAGACCATTCCTTTAACCAAACGTGAG
TTTGATCTACTCAACGCTTTGCTGTCCAACATTAACCAAGTCATGACCCGAGAAGATTTGCTGGAGCATGTCTGGAAATA
TGAGCAAGAAACTGAAACTAATGTGGTTGATGTCTACATCCGCTATCTCCGCGGCAAGATTGATGTTCCTGGAAAGGAAA
GCTACATTCAAACGGTTCGCGGTATGGGTTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3VDK1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

80.349

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.686

100

0.677
  vicR Streptococcus mutans UA159

44.206

100

0.45
  micA Streptococcus pneumoniae Cp1015

43.723

100

0.441

Multiple sequence alignment