Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQL23_RS07585 Genome accession   NZ_LS483341
Coordinates   1561722..1563122 (-) Length   466 a.a.
NCBI ID   WP_060553640.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1556722..1568122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS07560 (NCTC7865_01524) - 1557124..1557717 (-) 594 WP_060553637.1 class I SAM-dependent methyltransferase -
  DQL23_RS07565 (NCTC7865_01525) coaA 1557823..1558743 (+) 921 WP_048779535.1 type I pantothenate kinase -
  DQL23_RS07570 (NCTC7865_01526) rpsT 1558840..1559088 (+) 249 WP_008808726.1 30S ribosomal protein S20 -
  DQL23_RS07575 (NCTC7865_01527) - 1559319..1560770 (+) 1452 WP_060553638.1 alpha-amylase -
  DQL23_RS07580 (NCTC7865_01528) - 1560794..1561720 (-) 927 WP_060553639.1 ketopantoate reductase family protein -
  DQL23_RS07585 (NCTC7865_01529) ciaH 1561722..1563122 (-) 1401 WP_060553640.1 sensor histidine kinase Regulator
  DQL23_RS07590 (NCTC7865_01530) ciaR 1563112..1563786 (-) 675 WP_008808730.1 response regulator transcription factor Regulator
  DQL23_RS07595 (NCTC7865_01531) - 1563917..1564354 (-) 438 WP_060553641.1 hypothetical protein -
  DQL23_RS07600 (NCTC7865_01532) - 1564574..1565116 (+) 543 WP_060553642.1 biotin transporter BioY -
  DQL23_RS07605 (NCTC7865_01533) - 1565173..1567716 (-) 2544 WP_060553643.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 466 a.a.        Molecular weight: 53142.24 Da        Isoelectric Point: 9.5727

>NTDB_id=1137496 DQL23_RS07585 WP_060553640.1 1561722..1563122(-) (ciaH) [Streptococcus gordonii strain NCTC7865]
MLNKLRRTFYADDFSYFIRYFGVFTLIFSAMTLLIIQIMRSGLYTTVDDNLKSLSQNPRSVLHLALARAANMQPTIDEGQ
SSDDVSRPQDAPDPGPMDNLKVNSNTEAVLFDEDLKPLTTADHFLSLKKISIKKKDVGKIIQTTLKNNYGQEELYRMLVF
EINPSEFLSGNLLNKVKYAAVLINVNQLEQTSQNHEQIIVIVMISFWLISIIASIYLARVSVKPLMDSMQKQKSFVENAS
HELRTPLAVLQNRLETLFRKPEATIMESSENIASSLEEVRNMRMLTTNLLNLARRDDGIKAEIAEVEPEFFTTTFANYEI
IADENEKVFVFENHINHNIKTDRTLLKQLMTILFDNAVKYTEEDGVIKFIVWSKDRSLYLRVSDNGPGINNEDKKKIFDR
FYRVDKARTRQKGGFGLGLSLAKQIADALKGTITVKDNRPKGTIFEVKISIKSESKKKSTKLIGNK

Nucleotide


Download         Length: 1401 bp        

>NTDB_id=1137496 DQL23_RS07585 WP_060553640.1 1561722..1563122(-) (ciaH) [Streptococcus gordonii strain NCTC7865]
ATGCTGAATAAACTTAGACGAACTTTTTATGCGGATGATTTTTCATATTTCATTCGCTATTTTGGTGTATTCACACTGAT
TTTCTCGGCCATGACTCTTTTAATCATTCAGATTATGCGCTCAGGACTCTATACAACCGTTGACGATAATTTAAAAAGTT
TAAGTCAGAATCCCAGATCTGTTCTCCACCTTGCTTTGGCTCGTGCAGCCAATATGCAACCGACGATTGATGAAGGTCAG
TCATCTGATGATGTATCTAGACCACAAGACGCACCAGACCCTGGACCAATGGATAATCTGAAGGTGAATTCGAACACTGA
AGCTGTCTTGTTTGATGAAGACTTGAAACCATTGACTACTGCAGATCATTTTCTTAGTTTAAAAAAGATTTCAATCAAGA
AAAAGGATGTAGGTAAAATTATTCAGACTACTTTGAAAAACAACTATGGTCAAGAAGAACTCTATCGTATGTTGGTTTTT
GAGATTAATCCAAGCGAATTCTTATCTGGGAATCTTTTGAACAAAGTTAAATATGCAGCAGTCCTGATTAATGTCAATCA
GTTGGAGCAAACCAGTCAGAATCATGAACAGATTATTGTCATTGTTATGATTAGCTTTTGGTTAATCTCAATTATTGCTA
GTATCTATTTGGCTCGTGTCAGTGTGAAGCCTCTGATGGACAGTATGCAGAAACAAAAATCTTTTGTTGAAAATGCAAGC
CATGAGTTGCGTACTCCTTTAGCCGTTTTGCAAAACCGCTTGGAAACTCTTTTCCGAAAACCCGAAGCTACCATTATGGA
ATCAAGCGAAAATATTGCCTCCAGTCTGGAAGAAGTTCGGAATATGCGGATGCTAACAACTAATCTATTGAATCTTGCAA
GAAGAGATGATGGCATTAAGGCTGAAATTGCTGAAGTTGAACCAGAATTTTTCACTACAACATTTGCCAACTATGAAATC
ATTGCGGATGAAAACGAGAAAGTATTTGTCTTTGAAAACCATATTAACCACAATATCAAGACAGACAGAACACTTCTAAA
ACAGCTGATGACCATTCTCTTTGATAATGCTGTAAAATATACGGAAGAAGATGGGGTTATTAAGTTTATAGTATGGTCAA
AAGACCGTTCTCTTTACTTACGAGTGTCTGATAACGGACCTGGAATCAATAATGAAGACAAAAAGAAAATTTTTGATCGT
TTTTATAGGGTTGATAAAGCCAGAACAAGACAAAAGGGTGGTTTTGGTCTAGGTCTATCCCTTGCAAAACAAATTGCCGA
TGCTCTAAAGGGTACAATTACTGTTAAAGATAATAGACCGAAAGGTACCATTTTTGAAGTCAAAATTTCCATTAAATCAG
AAAGCAAGAAAAAATCAACTAAGCTAATAGGAAATAAATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(342-449)

His Kinase A (phospho-acceptor) domain (HisKA)

(233-298)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae D39

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae R6

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae TIGR4

66.594

98.283

0.655
  ciaH Streptococcus mutans UA159

54.343

96.352

0.524

Multiple sequence alignment