Detailed information NTG1136456

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQL15_RS00695
• Genome accession: NZ_LS483323
• Coordinates: 105456..105890 (+)
• Length: 144 a.a.
• NCBI ID: WP_002987783.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8300
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 100456..110890

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL15_RS00665 (NCTC8300_00134)	-	102125..102490 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQL15_RS00670 (NCTC8300_00135)	comYA	102583..103521 (+)	939	WP_002987773.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL15_RS00675 (NCTC8300_00136)	comYB	103457..104491 (+)	1035	WP_223845212.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL15_RS00680 (NCTC8300_00137)	comYC	104493..104819 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL15_RS00685 (NCTC8300_00138)	comGD	104794..105222 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQL15_RS00690 (NCTC8300_00139)	comGE	105179..105463 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
DQL15_RS00695 (NCTC8300_00140)	comYF	105456..105890 (+)	435	WP_002987783.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL15_RS00700 (NCTC8300_00141)	comGG	105874..106200 (+)	327	WP_002987787.1	competence type IV pilus minor pilin ComGG	-
DQL15_RS00705 (NCTC8300_00142)	comYH	106298..107251 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
DQL15_RS00710 (NCTC8300_00143)	-	107310..108506 (+)	1197	WP_002987791.1	acetate kinase	-
DQL15_RS00715	-	108693..109001 (+)	309	WP_011284425.1	hypothetical protein	-
DQL15_RS00720 (NCTC8300_00144)	proC	109084..109854 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16585.23 Da
• Isoelectric Point: 10.2064

>NTDB_id=1136456 DQL15_RS00695 WP_002987783.1 105456..105890(+) (comYF) [Streptococcus pyogenes strain NCTC8300]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1136456 DQL15_RS00695 WP_002987783.1 105456..105890(+) (comYF) [Streptococcus pyogenes strain NCTC8300]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396