Detailed information NTG1136176

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQM44_RS00345
• Genome accession: NZ_LS483318
• Coordinates: 54597..55508 (+)
• Length: 303 a.a.
• NCBI ID: WP_012766420.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 49597..60508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM44_RS00325 (NCTC5370_00066)	purE	51101..51589 (+)	489	WP_022554085.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQM44_RS00330 (NCTC5370_00067)	purK	51576..52658 (+)	1083	WP_022554086.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQM44_RS00335 (NCTC5370_00068)	-	52787..53014 (+)	228	WP_022554087.1	hypothetical protein	-
DQM44_RS00340 (NCTC5370_00069)	purB	53162..54454 (+)	1293	WP_022554088.1	adenylosuccinate lyase	-
DQM44_RS00345 (NCTC5370_00070)	comR	54597..55508 (+)	912	WP_012766420.1	XRE family transcriptional regulator	Regulator
DQM44_RS10550 (NCTC5370_00071)	comS	55595..55690 (+)	96	WP_198455558.1	quorum-sensing system DWW-type pheromone	Regulator
DQM44_RS00350 (NCTC5370_00072)	ruvB	55743..56741 (+)	999	WP_022554089.1	Holliday junction branch migration DNA helicase RuvB	-
DQM44_RS00355 (NCTC5370_00073)	-	56876..57307 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
DQM44_RS00360 (NCTC5370_00074)	-	57336..57737 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
DQM44_RS00365 (NCTC5370_00075)	-	57734..59509 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35726.31 Da
• Isoelectric Point: 4.5798

>NTDB_id=1136176 DQM44_RS00345 WP_012766420.1 54597..55508(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEQLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKLRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKIIIDISSLSIKTNKLDNLEKTIAISQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide

• Length: 912 bp

>NTDB_id=1136176 DQM44_RS00345 WP_012766420.1 54597..55508(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAACAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTAAGTG
AAAACATCAATTTTGGTGTCGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAACTACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAATTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGGCA
AAAATCCAGGATTGGAATAGAATGCCTATACTAAAATTAATAGAATGGAAGTACTTTTTAATAAAACAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAAATAACAGGAGACAAGTATTTGGAAGAGCAATTAATCA
AAGAATGGGAGAAAGATATTTGTGCTTATTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	82.178	100	0.822
comR	Streptococcus pyogenes MGAS315	54.667	99.01	0.541
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	50.847	97.36	0.495
comR	Streptococcus mutans UA159	49.498	98.68	0.488