Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQL11_RS07770 Genome accession   NZ_LS483315
Coordinates   1516753..1517439 (-) Length   228 a.a.
NCBI ID   WP_002991052.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12059     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1511753..1522439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL11_RS07750 (NCTC12059_01544) dnaI 1512474..1513376 (-) 903 WP_111704772.1 primosomal protein DnaI -
  DQL11_RS07755 (NCTC12059_01545) - 1513377..1514552 (-) 1176 WP_009880401.1 replication initiation and membrane attachment family protein -
  DQL11_RS07760 (NCTC12059_01546) nrdR 1514536..1515030 (-) 495 WP_002985941.1 transcriptional regulator NrdR -
  DQL11_RS07765 (NCTC12059_01547) covS 1515245..1516747 (-) 1503 WP_002985946.1 two-component system sensor histidine kinase CovS -
  DQL11_RS07770 (NCTC12059_01548) covR 1516753..1517439 (-) 687 WP_002991052.1 two-component system response regulator CovR Regulator
  DQL11_RS07775 (NCTC12059_01549) - 1517706..1518239 (-) 534 WP_032464180.1 YceD family protein -
  DQL11_RS07780 (NCTC12059_01550) htpX 1518473..1519369 (-) 897 WP_111704773.1 zinc metalloprotease HtpX -
  DQL11_RS07785 (NCTC12059_01551) - 1519416..1519973 (-) 558 WP_111704774.1 LemA family protein -
  DQL11_RS07790 (NCTC12059_01552) rsmG 1520123..1520836 (+) 714 WP_014407313.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQL11_RS07795 (NCTC12059_01553) ktrB 1520921..1522297 (+) 1377 WP_033887684.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26618.70 Da        Isoelectric Point: 4.6586

>NTDB_id=1136080 DQL11_RS07770 WP_002991052.1 1516753..1517439(-) (covR) [Streptococcus pyogenes strain NCTC12059]
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1136080 DQL11_RS07770 WP_002991052.1 1516753..1517439(-) (covR) [Streptococcus pyogenes strain NCTC12059]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
CGAAGTCATTGTTGAGGTCAATGGTCGTGAAGGGTTAGAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACGTATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGATATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGCATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.966

100

0.447
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment