Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JM183_RS04355 Genome accession   NZ_LR962863
Coordinates   958573..959202 (+) Length   209 a.a.
NCBI ID   WP_016425506.1    Uniprot ID   S2XKD5
Organism   Staphylococcus schleiferi strain NCTC12218     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 953573..964202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JM183_RS04330 (NCTC12218_00920) - 954485..955483 (-) 999 Protein_860 FUSC family protein -
  JM183_RS04335 (NCTC12218_00921) map 955581..956342 (+) 762 WP_016425510.1 type I methionyl aminopeptidase -
  JM183_RS04340 (NCTC12218_00922) - 956440..956829 (+) 390 WP_016425509.1 hypothetical protein -
  JM183_RS04345 (NCTC12218_00923) liaF 956842..957543 (+) 702 WP_016425508.1 cell wall-active antibiotics response protein LiaF -
  JM183_RS04350 (NCTC12218_00924) vraS 957540..958583 (+) 1044 WP_050330549.1 sensor histidine kinase Regulator
  JM183_RS04355 (NCTC12218_00925) vraR 958573..959202 (+) 630 WP_016425506.1 response regulator transcription factor Regulator
  JM183_RS04360 (NCTC12218_00926) - 959257..959829 (-) 573 WP_016425505.1 beta-class carbonic anhydrase -
  JM183_RS04365 (NCTC12218_00928) - 959862..961122 (-) 1261 Protein_867 YihY/virulence factor BrkB family protein -
  JM183_RS04370 (NCTC12218_00929) - 961413..961700 (-) 288 WP_016425503.1 YtxH domain-containing protein -
  JM183_RS04375 (NCTC12218_00930) - 961708..962166 (-) 459 WP_016425502.1 low molecular weight protein-tyrosine-phosphatase -
  JM183_RS04380 (NCTC12218_00931) - 962299..962502 (+) 204 WP_016425501.1 DUF1128 family protein -
  JM183_RS04385 (NCTC12218_00932) - 962521..963753 (+) 1233 WP_016425500.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23479.04 Da        Isoelectric Point: 5.0018

>NTDB_id=1134902 JM183_RS04355 WP_016425506.1 958573..959202(+) (vraR) [Staphylococcus schleiferi strain NCTC12218]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAIQKAHELHPDLILMDLVMTDMDGVEATTQIKKDLPHIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIAEAIRKTSQGESVFEAEVLVKMRNRMKQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1134902 JM183_RS04355 WP_016425506.1 958573..959202(+) (vraR) [Staphylococcus schleiferi strain NCTC12218]
ATGACAATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGAATATCTAGCTATTTATCCACGCAACCGGA
TATTGAGGTTGTAGGGGAAGGGGCTTCAGGGAAAGAGGCTATTCAAAAAGCACATGAACTTCATCCGGATTTAATTTTAA
TGGACTTAGTGATGACAGACATGGACGGTGTTGAAGCGACAACACAAATCAAAAAAGACTTACCACATATTAAAGTGGTC
ATGCTTACAAGTTATATTGAGGATAAAGAAGTTTATCGTGCCTTAGATGCAGGTGTCGATAGTTATATTCTTAAAACGAC
AAGTGCAAGTGATATTGCTGAAGCGATACGAAAAACAAGTCAAGGCGAGTCTGTATTTGAAGCAGAAGTCCTTGTGAAAA
TGCGCAATCGCATGAAACAAAGAGCGGAATTATATGAGTTACTGACAGAGCGTGAAATGGAAATCCTATTATTGATATCA
AAAGGGTATTCAAATCAAGAAATCGCAAGTGCTTCACATATTACGATTAAAACAGTGAAAACACATGTGAGTAATATTTT
AAGTAAATTAGAAGTGCAAGATCGTACGCAAGCAGTGATTTATGCCTTTCAACATGGATTAATTGAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S2XKD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

91.388

100

0.914
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment