Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   H1X63_RS04280 Genome accession   NZ_LR822027
Coordinates   816935..818353 (+) Length   472 a.a.
NCBI ID   WP_179974451.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_998     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 811935..823353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X63_RS04255 (STHERMO_0885) - 812383..812970 (-) 588 WP_180487811.1 ECF transporter S component -
  H1X63_RS04260 (STHERMO_0886) coaC 812998..813543 (-) 546 WP_179972889.1 phosphopantothenoylcysteine decarboxylase -
  H1X63_RS04265 (STHERMO_0887) - 813536..814219 (-) 684 WP_179974449.1 phosphopantothenate--cysteine ligase -
  H1X63_RS04270 (STHERMO_0888) - 814413..816083 (+) 1671 WP_180487803.1 formate--tetrahydrofolate ligase -
  H1X63_RS04275 (STHERMO_0889) ciaR 816271..816945 (+) 675 WP_179974450.1 response regulator transcription factor Regulator
  H1X63_RS04280 (STHERMO_0890) ciaH 816935..818353 (+) 1419 WP_179974451.1 sensor histidine kinase Regulator
  H1X63_RS04285 (STHERMO_0891) rpsT 818441..818677 (-) 237 WP_179972893.1 30S ribosomal protein S20 -
  H1X63_RS04290 (STHERMO_0892) coaA 818746..819666 (-) 921 WP_179972894.1 type I pantothenate kinase -
  H1X63_RS04295 (STHERMO_0893) - 819974..820564 (+) 591 WP_179972895.1 class I SAM-dependent methyltransferase -
  H1X63_RS04305 - 820561..821804 (+) 1244 Protein_800 pyrimidine-nucleoside phosphorylase -
  H1X63_RS04310 (STHERMO_0899) deoC 821890..822534 (+) 645 WP_179972996.1 deoxyribose-phosphate aldolase -
  H1X63_RS04315 (STHERMO_0900) - 822521..822919 (+) 399 WP_179972997.1 cytidine deaminase -

Sequence

Protein


Download         Length: 472 a.a.        Molecular weight: 53807.74 Da        Isoelectric Point: 9.0583

>NTDB_id=1131342 H1X63_RS04280 WP_179974451.1 816935..818353(+) (ciaH) [Streptococcus thermophilus isolate STH_CIRM_998]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILRYGVYSNVDSSLKEAVTKTNSYLEMEMLKREFFLTSD
VDQNNTATIYQEYDSKASLDKIPNSGVYKTKSKKIKSKIEDAPHDLTVAANTSVLVLDKNGKALNVVDKFSSLSNLPIDK
NTIDVISKGSAQNYFDQTENYRLITEKVDNSFYPDAKYVVIAINTTQLEEATERYVKLIVIMMSFFWLLSIAASLYLAKW
SRRPIQESLEKQKTFVENASHELRTPLAVIQNRLESLFRKPESTILDNSENIAYSLDEVRNMRLLTTNLLNLTRRDDGIK
PEIETLDSSFFDKVFTNYATIAEESEKVFTAQNQVGRSIKTDKTLLKQLMTILFDNAIKYTEDDGQVILAVRTNDRHLYI
TVADNGPGIADEDKKKIFDRFYCVDKARTRQKGGFGLGLSLAQQIVLALKGTIIVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1419 bp        

>NTDB_id=1131342 H1X63_RS04280 WP_179974451.1 816935..818353(+) (ciaH) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGCTGACTAAATTTTTCAATTATCTCTTCAGGAGAATCAAGTCAGACGGCTTTAAGTCCTTCATCCATTTCTTTGCAAC
TTTTTCTGGTATTTTCCTTATCATGACTGTTATGATATTGCAGATTCTCAGATATGGAGTTTATTCCAATGTTGACTCTA
GTCTGAAAGAAGCAGTAACTAAGACCAATTCTTATTTGGAAATGGAAATGCTAAAACGCGAATTTTTTCTGACTTCTGAT
GTAGATCAAAATAATACGGCAACTATCTATCAGGAGTATGATAGCAAAGCATCGCTAGACAAAATACCTAATTCGGGTGT
TTATAAGACAAAATCTAAAAAGATCAAATCAAAAATCGAAGATGCTCCTCATGATTTGACTGTAGCAGCTAATACTAGTG
TGTTAGTTCTTGATAAGAATGGAAAGGCCCTAAACGTTGTCGACAAATTTTCTAGCTTATCTAATTTACCAATAGATAAA
AATACTATTGATGTTATTAGTAAGGGGAGTGCTCAGAACTACTTTGATCAAACGGAAAATTATCGCTTGATTACTGAAAA
AGTAGATAATAGTTTCTATCCTGATGCTAAGTACGTTGTTATCGCAATCAATACGACGCAATTAGAAGAAGCCACTGAAC
GTTATGTAAAACTAATTGTCATTATGATGAGTTTTTTTTGGCTACTATCTATCGCGGCTAGTTTGTATTTGGCAAAATGG
TCAAGACGGCCTATACAGGAAAGTCTTGAGAAGCAGAAGACATTTGTTGAGAATGCTAGCCACGAGTTGCGTACGCCACT
TGCTGTGATTCAAAACCGTCTAGAGTCTCTTTTCCGCAAGCCAGAGTCTACAATTTTAGACAATTCAGAGAACATTGCTT
ATAGTCTAGATGAAGTCCGAAATATGCGTCTTTTGACGACCAATCTCTTGAATTTGACTCGTCGTGATGATGGTATTAAA
CCAGAAATTGAAACTCTAGATTCCTCTTTCTTTGATAAAGTCTTTACCAATTATGCTACGATTGCTGAAGAAAGTGAAAA
GGTGTTTACTGCTCAAAATCAGGTTGGGCGCTCAATCAAAACTGATAAGACTCTATTGAAGCAGCTCATGACAATTTTAT
TTGATAATGCTATCAAATATACAGAAGATGATGGCCAGGTGATCCTCGCCGTTCGTACTAATGATCGTCATCTTTATATT
ACAGTGGCAGACAATGGCCCTGGTATTGCAGATGAAGATAAGAAAAAAATCTTTGATCGTTTCTACTGTGTAGACAAAGC
TAGAACTAGACAAAAAGGTGGTTTTGGGTTGGGCTTATCTTTGGCACAACAGATTGTTCTTGCACTTAAAGGAACAATAA
TTGTCAAGGACAATCAGCCGAAGGGGACTATTTTTGAAGTTAAAATTACCGGAGTCTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(253-318)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(362-469)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

55.628

97.881

0.544
  ciaH Streptococcus pneumoniae Rx1

49.462

98.517

0.487
  ciaH Streptococcus pneumoniae D39

49.462

98.517

0.487
  ciaH Streptococcus pneumoniae R6

49.462

98.517

0.487
  ciaH Streptococcus pneumoniae TIGR4

49.462

98.517

0.487

Multiple sequence alignment