Detailed information NTG1131294

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H1W98_RS07865
• Genome accession: NZ_LR822026
• Coordinates: 1529648..1531888 (-)
• Length: 746 a.a.
• NCBI ID: WP_179972172.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_967
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1524648..1536888

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W98_RS07845 (STHERMO_1778)	-	1525512..1526372 (-)	861	WP_002951571.1	methionyl aminopeptidase	-
H1W98_RS07850 (STHERMO_1779)	spxR	1526416..1527696 (-)	1281	WP_179972170.1	CBS-HotDog domain-containing transcription factor SpxR	-
H1W98_RS07855	-	1527689..1528234 (-)	546	Protein_1499	GNAT family N-acetyltransferase	-
H1W98_RS07860 (STHERMO_1782)	-	1528300..1529562 (-)	1263	WP_179972171.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W98_RS07865 (STHERMO_1783)	comEC/celB	1529648..1531888 (-)	2241	WP_179972172.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H1W98_RS07870 (STHERMO_1784)	comEA	1531878..1532573 (-)	696	WP_180482451.1	helix-hairpin-helix domain-containing protein	Machinery gene
H1W98_RS07875 (STHERMO_1785)	-	1532680..1533435 (-)	756	WP_180482450.1	lysophospholipid acyltransferase family protein	-
H1W98_RS11245	-	1533565..1534474 (+)	910	Protein_1504	polysaccharide deacetylase family protein	-
H1W98_RS07885 (STHERMO_1788)	-	1534524..1535288 (+)	765	WP_180482449.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H1W98_RS07890 (STHERMO_1789)	-	1535292..1535561 (+)	270	WP_180482448.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84981.00 Da
• Isoelectric Point: 9.9593

>NTDB_id=1131294 H1W98_RS07865 WP_179972172.1 1529648..1531888(-) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_967]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYNIAIMQDKQ
APAEIHQVTLVADTLSVNGERLSAIGKSNGQTYRVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIERLEHVVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNPLFEWMEFFLTWIQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFVSKEKWQEGSQTSNAEKTLIPYLQERGVSQIDYLVLTHTDT
DHIGDLEEVAKRFKIKEICVSKGALTKPSFAKRIRFLKRPVRTLKAGDKLTMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMASYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDLDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1131294 H1W98_RS07865 WP_179972172.1 1529648..1531888(-) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_967]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACAATATAGCTATCATGCAAGATAAACAA
GCTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCGGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACGAGTCAAA
CGCTTGTTTTAAAAGGAAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGTCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAATCCACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GATACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
GACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGTCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATTTACAGGAAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GATCATATTGGTGATTTGGAGGAAGTGGCTAAACGGTTTAAGATTAAGGAAATTTGTGTCAGTAAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAACGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGACTATGATGG
GAAGTAACCTACAGGTTCTTTATCCTAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTTTGTTTACTGGTGATTTAGAAAAAGAAGGAGAGGAGGAATTAATGGCTAGCTATCCAAATTTAAA
AGTAAGGGTCCTAAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCTGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCTGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus mitis SK321	46.791	100	0.469
comEC/celB	Streptococcus pneumoniae TIGR4	46.123	100	0.462
comEC/celB	Streptococcus pneumoniae Rx1	45.856	100	0.46
comEC/celB	Streptococcus pneumoniae D39	45.856	100	0.46
comEC/celB	Streptococcus pneumoniae R6	45.856	100	0.46
comEC	Lactococcus lactis subsp. cremoris KW2	44.69	97.185	0.434