Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H1W98_RS01725 Genome accession   NZ_LR822026
Coordinates   324147..324836 (+) Length   229 a.a.
NCBI ID   WP_180482244.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_967     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 319147..329836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W98_RS10555 (STHERMO_0352) - 320111..320262 (+) 152 Protein_294 ascorbate 6-phosphate lactonase -
  H1W98_RS01705 (STHERMO_0353) - 320300..320971 (-) 672 WP_100284858.1 potassium channel family protein -
  H1W98_RS01710 (STHERMO_0354) - 321011..322375 (-) 1365 WP_269473099.1 TrkH family potassium uptake protein -
  H1W98_RS01715 (STHERMO_0355) rsmG 322445..323158 (-) 714 WP_100284860.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H1W98_RS01720 (STHERMO_0356) - 323455..323991 (+) 537 WP_179974237.1 DUF177 domain-containing protein -
  H1W98_RS01725 (STHERMO_0357) covR 324147..324836 (+) 690 WP_180482244.1 response regulator transcription factor Regulator
  H1W98_RS01730 (STHERMO_0358) covS 324833..326350 (+) 1518 WP_179972619.1 HAMP domain-containing histidine kinase Regulator
  H1W98_RS01735 (STHERMO_0359) nrdR 326472..326951 (+) 480 WP_179972620.1 transcriptional regulator NrdR -
  H1W98_RS01740 (STHERMO_0360) - 326948..328123 (+) 1176 WP_179972621.1 DnaD domain protein -
  H1W98_RS01745 (STHERMO_0361) dnaI 328127..329029 (+) 903 WP_100284865.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26583.70 Da        Isoelectric Point: 4.7703

>NTDB_id=1131263 H1W98_RS01725 WP_180482244.1 324147..324836(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_967]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRGR

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1131263 H1W98_RS01725 WP_180482244.1 324147..324836(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_967]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGCCAAGATATTGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGGAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

96.476

99.127

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

45.064

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment