Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   H0513_RS04425 Genome accession   NZ_LR822023
Coordinates   830580..831998 (+) Length   472 a.a.
NCBI ID   WP_179972892.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_368     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 825580..836998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0513_RS04400 (STHERMO_0946) - 826042..826614 (-) 573 WP_179972994.1 ECF transporter S component -
  H0513_RS04405 (STHERMO_0947) coaC 826642..827187 (-) 546 WP_179972889.1 phosphopantothenoylcysteine decarboxylase -
  H0513_RS04410 (STHERMO_0948) - 827180..827863 (-) 684 WP_002948206.1 phosphopantothenate--cysteine ligase -
  H0513_RS04415 (STHERMO_0949) - 828057..829727 (+) 1671 WP_179972890.1 formate--tetrahydrofolate ligase -
  H0513_RS04420 (STHERMO_0950) ciaR 829916..830590 (+) 675 WP_179972891.1 response regulator transcription factor Regulator
  H0513_RS04425 (STHERMO_0951) ciaH 830580..831998 (+) 1419 WP_179972892.1 sensor histidine kinase Regulator
  H0513_RS04430 (STHERMO_0952) rpsT 832086..832322 (-) 237 WP_179972893.1 30S ribosomal protein S20 -
  H0513_RS04435 (STHERMO_0953) coaA 832391..833311 (-) 921 WP_179972894.1 type I pantothenate kinase -
  H0513_RS04440 (STHERMO_0954) - 833619..834209 (+) 591 WP_179972895.1 class I SAM-dependent methyltransferase -
  H0513_RS04450 - 834206..835449 (+) 1244 Protein_822 pyrimidine-nucleoside phosphorylase -
  H0513_RS04455 (STHERMO_0960) deoC 835535..836179 (+) 645 WP_179972996.1 deoxyribose-phosphate aldolase -
  H0513_RS04460 (STHERMO_0961) - 836166..836564 (+) 399 WP_179972997.1 cytidine deaminase -

Sequence

Protein


Download         Length: 472 a.a.        Molecular weight: 53839.80 Da        Isoelectric Point: 9.0583

>NTDB_id=1131150 H0513_RS04425 WP_179972892.1 830580..831998(+) (ciaH) [Streptococcus thermophilus isolate STH_CIRM_368]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILRYGVYSNVDSSLKEAVTKTNSYLEMEMLKREFFLTSD
VDQNNTATIYQEYDSKASLDKIPNSGVYKTKSKKIKSKIEDAPHDLTVAANTSVLVLDKNGKALNVVDKFSSLSNLPIDK
NTIDVISKGSAQNYFDQTENYRLITEKVDNSFYPDAKYVVIAINTTQLEEATERYVKLIVIMMSFFWLLSIAASLYLAKW
SRRPIQESLEKQKTFVENASHELRTPLAMIQNRLESLFRKPESTILDNSENIAYSLDEVRNMRLLTTNLLNLTRRDDGIK
PEIETLDSSFFDKVFTNYATIAEESEKVFTAQNQVGRSIKTDKTLLKQLMTILFDNAIKYTEDDGQVILAVRTNDRHLYI
TVADNGPGIADEDKKKIFDRFYCVDKARTRQKGGFGLGLSLAQQIVLALKGTIIVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1419 bp        

>NTDB_id=1131150 H0513_RS04425 WP_179972892.1 830580..831998(+) (ciaH) [Streptococcus thermophilus isolate STH_CIRM_368]
ATGCTGACTAAATTTTTCAATTATCTCTTCAGGAGAATCAAGTCAGACGGCTTTAAGTCCTTCATCCATTTCTTTGCAAC
TTTTTCTGGTATTTTCCTTATCATGACTGTTATGATATTGCAGATTCTCAGATATGGAGTTTATTCCAATGTTGACTCTA
GTCTGAAAGAAGCAGTAACTAAGACCAATTCTTATTTGGAAATGGAAATGCTAAAACGCGAATTTTTTCTGACTTCTGAT
GTAGATCAAAATAATACGGCAACTATCTATCAGGAGTATGATAGCAAAGCATCGCTAGACAAAATACCTAATTCGGGTGT
TTATAAGACAAAATCTAAAAAGATCAAATCAAAAATCGAAGATGCTCCTCATGATTTGACTGTAGCAGCTAATACTAGTG
TGTTAGTTCTTGATAAGAATGGAAAGGCCCTAAACGTTGTCGACAAATTTTCTAGCTTATCTAATTTACCAATAGATAAA
AATACTATTGATGTTATTAGTAAGGGGAGTGCTCAGAACTACTTTGATCAAACGGAAAATTATCGCTTGATTACTGAAAA
AGTAGATAATAGTTTCTATCCTGATGCTAAGTACGTTGTTATCGCAATCAATACGACGCAATTAGAAGAAGCCACTGAAC
GTTATGTAAAACTAATTGTCATTATGATGAGTTTTTTTTGGCTACTATCTATCGCGGCTAGTTTGTATTTGGCAAAATGG
TCAAGACGGCCTATACAGGAAAGTCTTGAGAAGCAGAAGACATTTGTTGAGAATGCTAGCCACGAGTTGCGTACGCCACT
TGCTATGATTCAAAACCGTCTAGAGTCTCTTTTCCGCAAGCCAGAGTCTACAATTTTAGACAATTCAGAGAACATTGCTT
ATAGTCTAGATGAAGTCCGAAATATGCGTCTTTTGACGACCAATCTCTTGAATTTGACTCGTCGTGATGATGGTATTAAA
CCAGAAATTGAAACTCTAGATTCCTCTTTCTTTGATAAAGTCTTTACCAATTATGCTACGATTGCTGAAGAAAGTGAAAA
GGTGTTTACTGCTCAAAATCAGGTTGGGCGCTCAATCAAAACTGATAAGACTCTATTGAAGCAGCTCATGACAATTTTAT
TTGATAATGCTATCAAATATACAGAAGATGATGGCCAGGTGATCCTCGCCGTTCGTACTAATGATCGTCATCTTTATATT
ACAGTGGCAGACAATGGCCCTGGTATTGCAGATGAAGATAAGAAAAAAATCTTTGATCGTTTCTACTGTGTAGACAAAGC
TAGAACTAGACAAAAAGGTGGTTTTGGGTTGGGCTTATCTTTGGCACAACAGATTGTTCTTGCACTTAAAGGAACAATAA
TTGTCAAGGACAATCAGCCGAAGGGGACTATTTTTGAAGTTAAAATTACCGGAGTCTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(253-318)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(362-469)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

55.411

97.881

0.542
  ciaH Streptococcus pneumoniae Rx1

49.247

98.517

0.485
  ciaH Streptococcus pneumoniae D39

49.247

98.517

0.485
  ciaH Streptococcus pneumoniae R6

49.247

98.517

0.485
  ciaH Streptococcus pneumoniae TIGR4

49.247

98.517

0.485

Multiple sequence alignment