Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   H0514_RS05840 Genome accession   NZ_LR822020
Coordinates   1133535..1135022 (-) Length   495 a.a.
NCBI ID   WP_179973133.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1128535..1140022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS05805 (STHERMO_1337) - 1128969..1129367 (-) 399 WP_179972997.1 cytidine deaminase -
  H0514_RS05810 (STHERMO_1338) deoC 1129354..1129998 (-) 645 WP_179972996.1 deoxyribose-phosphate aldolase -
  H0514_RS05815 - 1130084..1131327 (-) 1244 Protein_1097 pyrimidine-nucleoside phosphorylase -
  H0514_RS05825 (STHERMO_1344) - 1131324..1131914 (-) 591 WP_179972895.1 class I SAM-dependent methyltransferase -
  H0514_RS05830 (STHERMO_1345) coaA 1132222..1133142 (+) 921 WP_179972894.1 type I pantothenate kinase -
  H0514_RS05835 (STHERMO_1346) rpsT 1133211..1133447 (+) 237 WP_179972893.1 30S ribosomal protein S20 -
  H0514_RS05840 (STHERMO_1347) ciaH 1133535..1135022 (-) 1488 WP_179973133.1 sensor histidine kinase Regulator
  H0514_RS05845 (STHERMO_1348) ciaR 1135012..1135686 (-) 675 WP_179972891.1 response regulator transcription factor Regulator
  H0514_RS05850 (STHERMO_1349) - 1135875..1137545 (-) 1671 WP_179973134.1 formate--tetrahydrofolate ligase -
  H0514_RS05855 (STHERMO_1350) - 1137739..1138422 (+) 684 WP_002948206.1 phosphopantothenate--cysteine ligase -
  H0514_RS05860 (STHERMO_1351) coaC 1138415..1138960 (+) 546 WP_179972889.1 phosphopantothenoylcysteine decarboxylase -
  H0514_RS05865 (STHERMO_1352) - 1138988..1139560 (+) 573 WP_179972994.1 ECF transporter S component -

Sequence

Protein


Download         Length: 495 a.a.        Molecular weight: 56478.83 Da        Isoelectric Point: 9.3226

>NTDB_id=1131095 H0514_RS05840 WP_179973133.1 1133535..1135022(-) (ciaH) [Streptococcus thermophilus isolate STH_CIRM_956]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILRYGVYSNVDSSLKEAVTKTNSYLEMEMLKREFFLTSD
VDQNNTATIYQEYDSKASLDKIPNSGVYKTKSKKIKSKIEDAPHDLTVAANTSVLVLDKNGKALNVVDKFSSLSNLPIDK
NTIDVISKGSAQNYFDQTENYRLITEKVDNSFYPDAKYVVIAINTTQLEEATERYVKLIVIMMSFFWLLSIAASLYLAKW
SRRPIQESLEKQTIAASLYLAKWSRRPIQESLEKQKTFVENASHELRTPLAVIQNRLESLFRKPESTILDNSENIAYSLD
EVRNMRLLTTNLLNLTRRDDGIKPEIETLDSSFFDKVFTNYATIAEESEKVFTAQNQVGRSIKTDKTLLKQLMTILFDNA
IKYTEDDGQVILAVRTNDRHLYITVADNGPGIADEDKKKIFDRFYCVDKARTRQKGGFGLGLSLAQQIVLALKGTIIVKD
NQPKGTIFEVKITGV

Nucleotide


Download         Length: 1488 bp        

>NTDB_id=1131095 H0514_RS05840 WP_179973133.1 1133535..1135022(-) (ciaH) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGCTGACTAAATTTTTCAATTATCTCTTCAGGAGAATCAAGTCAGACGGCTTTAAGTCCTTCATCCATTTCTTTGCAAC
TTTTTCTGGTATTTTCCTTATCATGACTGTTATGATATTGCAGATTCTCAGATATGGAGTTTATTCCAATGTTGACTCTA
GTCTGAAAGAAGCAGTAACTAAGACCAATTCTTATTTGGAAATGGAAATGCTAAAACGCGAATTTTTTCTGACTTCTGAT
GTAGATCAAAATAATACGGCAACTATCTATCAGGAGTATGATAGCAAAGCATCGCTAGACAAAATACCTAATTCGGGTGT
TTATAAGACAAAATCTAAAAAGATCAAATCAAAAATCGAAGATGCTCCTCATGATTTGACTGTAGCAGCTAATACTAGTG
TGTTAGTTCTTGATAAGAATGGAAAGGCCCTAAACGTTGTCGACAAATTTTCTAGCTTATCTAATTTACCAATAGATAAA
AATACTATTGATGTTATTAGTAAGGGGAGTGCTCAGAACTACTTTGATCAAACGGAAAATTATCGCTTGATTACTGAAAA
AGTAGATAATAGTTTCTATCCTGATGCTAAGTACGTTGTTATCGCAATCAATACGACGCAATTAGAAGAAGCCACTGAAC
GTTATGTAAAACTAATTGTCATTATGATGAGTTTTTTTTGGCTACTATCTATCGCGGCTAGTTTGTATTTGGCAAAATGG
TCAAGACGGCCTATACAGGAAAGTCTTGAGAAGCAGACTATCGCGGCTAGTTTGTATTTGGCAAAATGGTCAAGACGGCC
TATACAGGAAAGTCTTGAGAAGCAGAAGACATTTGTTGAGAATGCTAGCCACGAGTTGCGTACGCCACTTGCTGTGATTC
AAAACCGTCTAGAGTCTCTTTTCCGCAAGCCAGAGTCTACAATTTTAGACAATTCAGAGAACATTGCTTATAGTCTAGAT
GAAGTCCGAAATATGCGTCTTTTGACGACCAATCTCTTGAATTTGACTCGTCGTGATGATGGTATTAAACCAGAAATTGA
AACTCTAGATTCCTCTTTCTTTGATAAAGTCTTTACCAATTATGCTACGATTGCTGAAGAAAGTGAAAAGGTGTTTACTG
CTCAAAATCAGGTTGGGCGCTCAATCAAAACTGATAAGACTCTATTGAAGCAGCTCATGACAATTTTATTTGATAATGCT
ATCAAATATACAGAAGATGATGGCCAGGTGATCCTCGCCGTTCGTACTAATGATCGTCATCTTTATATTACAGTGGCAGA
CAATGGCCCTGGTATTGCAGATGAAGATAAGAAAAAAATCTTTGATCGTTTCTACTGTGTAGACAAAGCTAGAACTAGAC
AAAAAGGTGGTTTTGGGTTGGGCTTATCTTTGGCACAACAGATTGTTCTTGCACTTAAAGGAACAATAATTGTCAAGGAC
AATCAGCCGAAGGGGACTATTTTTGAAGTTAAAATTACCGGAGTCTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(276-341)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(385-492)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

52.99

97.98

0.519
  ciaH Streptococcus pneumoniae Rx1

46.626

98.788

0.461
  ciaH Streptococcus pneumoniae D39

46.626

98.788

0.461
  ciaH Streptococcus pneumoniae R6

46.626

98.788

0.461
  ciaH Streptococcus pneumoniae TIGR4

46.626

98.788

0.461

Multiple sequence alignment