Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H0511_RS01675 Genome accession   NZ_LR822017
Coordinates   309982..310671 (+) Length   229 a.a.
NCBI ID   WP_179974238.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 304982..315671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS09730 (STHERMO_0326) - 305946..306118 (+) 173 Protein_277 ascorbate 6-phosphate lactonase -
  H0511_RS01655 (STHERMO_0327) - 306135..306806 (-) 672 WP_100284858.1 potassium channel family protein -
  H0511_RS01660 (STHERMO_0328) - 306846..308210 (-) 1365 WP_100284859.1 TrkH family potassium uptake protein -
  H0511_RS01665 (STHERMO_0329) rsmG 308280..308993 (-) 714 WP_100284860.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H0511_RS01670 (STHERMO_0330) - 309290..309826 (+) 537 WP_179974237.1 DUF177 domain-containing protein -
  H0511_RS01675 (STHERMO_0331) covR 309982..310671 (+) 690 WP_179974238.1 response regulator transcription factor Regulator
  H0511_RS01680 (STHERMO_0332) - 310668..312185 (+) 1518 Protein_283 ATP-binding protein -
  H0511_RS01685 (STHERMO_0333) nrdR 312307..312786 (+) 480 WP_179972620.1 transcriptional regulator NrdR -
  H0511_RS01690 (STHERMO_0334) - 312783..313958 (+) 1176 WP_179972621.1 DnaD domain protein -
  H0511_RS01695 (STHERMO_0335) dnaI 313962..314864 (+) 903 WP_100284865.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26654.78 Da        Isoelectric Point: 4.7059

>NTDB_id=1130954 H0511_RS01675 WP_179974238.1 309982..310671(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_336]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLNNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1130954 H0511_RS01675 WP_179974238.1 309982..310671(+) (covR) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGCCAAGATATTGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAATAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGATGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

96.07

100

0.961
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment