Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA3   Type   Regulator
Locus tag   H0506_RS06565 Genome accession   NZ_LR822015
Coordinates   1269856..1271823 (-) Length   655 a.a.
NCBI ID   WP_179971679.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_65     
Function   binding to XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1246206..1316312 1269856..1271823 within 0
IScluster/Tn 1268562..1275919 1269856..1271823 within 0


Gene organization within MGE regions


Location: 1246206..1316312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0506_RS06460 (STHERMO_1432) liaF 1246214..1246912 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H0506_RS09695 (STHERMO_1433) - 1247178..1247333 (-) 156 WP_011226290.1 ion channel -
  H0506_RS06470 (STHERMO_1436) stkP/pknB 1247970..1249841 (-) 1872 WP_011226292.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H0506_RS06475 (STHERMO_1437) - 1249841..1250578 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  H0506_RS06480 (STHERMO_1438) rsmB 1250622..1251944 (-) 1323 WP_014608533.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  H0506_RS06485 (STHERMO_1439) fmt 1251934..1252869 (-) 936 WP_002951411.1 methionyl-tRNA formyltransferase -
  H0506_RS06490 (STHERMO_1440) - 1252887..1255283 (-) 2397 WP_011226295.1 primosomal protein N' -
  H0506_RS06495 (STHERMO_1441) rpoZ 1255425..1255739 (-) 315 WP_002951415.1 DNA-directed RNA polymerase subunit omega -
  H0506_RS06500 (STHERMO_1442) gmk 1255761..1256390 (-) 630 WP_011226296.1 guanylate kinase -
  H0506_RS06505 (STHERMO_1443) ftsY 1256623..1258014 (-) 1392 WP_011226297.1 signal recognition particle-docking protein FtsY -
  H0506_RS06510 (STHERMO_1444) - 1258028..1258843 (-) 816 WP_011227405.1 Cof-type HAD-IIB family hydrolase -
  H0506_RS06515 (STHERMO_1445) - 1258836..1259630 (-) 795 WP_059257398.1 HAD hydrolase family protein -
  H0506_RS06520 (STHERMO_1446) - 1259813..1260190 (+) 378 WP_011226300.1 GntR family transcriptional regulator -
  H0506_RS06525 (STHERMO_1447) - 1260195..1260893 (+) 699 WP_011226301.1 ABC transporter ATP-binding protein -
  H0506_RS06530 (STHERMO_1448) - 1260905..1261690 (+) 786 WP_002951425.1 hypothetical protein -
  H0506_RS06535 (STHERMO_1449) amiF 1261740..1262669 (-) 930 WP_002951426.1 ATP-binding cassette domain-containing protein Regulator
  H0506_RS06540 (STHERMO_1450) amiE 1262662..1263747 (-) 1086 WP_011226304.1 ABC transporter ATP-binding protein Regulator
  H0506_RS06545 (STHERMO_1451) amiD 1263757..1264683 (-) 927 WP_002946409.1 oligopeptide ABC transporter permease OppC Regulator
  H0506_RS06550 (STHERMO_1452) amiC 1264683..1266176 (-) 1494 WP_011227407.1 ABC transporter permease Regulator
  H0506_RS06555 (STHERMO_1453) amiA 1266238..1268205 (-) 1968 WP_011225333.1 peptide ABC transporter substrate-binding protein Regulator
  H0506_RS09380 (STHERMO_1454) - 1268562..1269811 (+) 1250 Protein_1230 ISL3 family transposase -
  H0506_RS06565 (STHERMO_1455) amiA3 1269856..1271823 (-) 1968 WP_179971679.1 peptide ABC transporter substrate-binding protein Regulator
  H0506_RS06570 - 1272027..1272217 (-) 191 Protein_1232 IS3 family transposase -
  H0506_RS06575 (STHERMO_1456) - 1272211..1272621 (-) 411 Protein_1233 ATP-binding cassette domain-containing protein -
  H0506_RS06580 - 1272653..1272967 (-) 315 Protein_1234 TatD family hydrolase -
  H0506_RS06585 (STHERMO_1458) - 1273317..1274522 (+) 1206 WP_011227415.1 OFA family MFS transporter -
  H0506_RS06590 - 1274568..1275919 (-) 1352 Protein_1236 IS3 family transposase -
  H0506_RS06595 (STHERMO_1463) pta 1276005..1276988 (-) 984 WP_011226315.1 phosphate acetyltransferase -
  H0506_RS06600 (STHERMO_1464) - 1277002..1277898 (-) 897 WP_011226316.1 RluA family pseudouridine synthase -
  H0506_RS06605 (STHERMO_1465) - 1277895..1278731 (-) 837 WP_041827075.1 NAD kinase -
  H0506_RS06610 (STHERMO_1466) - 1278703..1279377 (-) 675 WP_002951443.1 GTP pyrophosphokinase family protein -
  H0506_RS06615 (STHERMO_1467) - 1279473..1280048 (+) 576 WP_002951444.1 CYTH domain-containing protein -
  H0506_RS06620 (STHERMO_1468) - 1280413..1281384 (+) 972 WP_002951446.1 ribose-phosphate diphosphokinase -
  H0506_RS06625 (STHERMO_1469) - 1281388..1282500 (+) 1113 WP_002948029.1 cysteine desulfurase family protein -
  H0506_RS06630 (STHERMO_1470) - 1282502..1282849 (+) 348 WP_011226321.1 DUF1831 domain-containing protein -
  H0506_RS06635 (STHERMO_1471) - 1282994..1283653 (+) 660 WP_041828288.1 redox-sensing transcriptional repressor Rex -
  H0506_RS06640 (STHERMO_1472) - 1283646..1284341 (+) 696 WP_011226323.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  H0506_RS06645 (STHERMO_1473) radC 1284394..1285080 (-) 687 WP_011226324.1 DNA repair protein RadC -
  H0506_RS06650 (STHERMO_1474) - 1285129..1286913 (-) 1785 WP_011226325.1 rhamnan synthesis F family protein -
  H0506_RS06655 (STHERMO_1475) - 1286910..1287965 (-) 1056 WP_179971680.1 glycosyltransferase -
  H0506_RS06660 (STHERMO_1476) - 1287985..1289190 (-) 1206 WP_011226326.1 ABC transporter ATP-binding protein -
  H0506_RS06665 (STHERMO_1477) - 1289190..1289999 (-) 810 WP_002948020.1 ABC transporter permease -
  H0506_RS06670 (STHERMO_1478) - 1289983..1290939 (-) 957 WP_011226328.1 glycosyltransferase family 2 protein -
  H0506_RS06675 (STHERMO_1479) cps2T 1290936..1292084 (-) 1149 WP_041828290.1 beta 1-4 rhamnosyltransferase Cps2T -
  H0506_RS06680 (STHERMO_1480) - 1292193..1293203 (-) 1011 WP_011226330.1 glycosyltransferase family A protein -
  H0506_RS06685 (STHERMO_1481) - 1293203..1294477 (-) 1275 WP_011226331.1 lipopolysaccharide biosynthesis protein -
  H0506_RS06690 (STHERMO_1482) - 1294470..1294802 (-) 333 WP_011226332.1 DUF2304 domain-containing protein -
  H0506_RS06695 (STHERMO_1483) - 1294808..1295503 (-) 696 WP_173940715.1 glycosyltransferase family 2 protein -
  H0506_RS06700 (STHERMO_1484) rfbD 1295580..1296431 (-) 852 WP_014621820.1 dTDP-4-dehydrorhamnose reductase -
  H0506_RS06705 (STHERMO_1485) - 1296508..1297842 (-) 1335 WP_041828293.1 DUF6056 family protein -
  H0506_RS06710 (STHERMO_1486) - 1297955..1298872 (-) 918 WP_002946425.1 glycosyltransferase family 2 protein -
  H0506_RS06715 (STHERMO_1487) - 1298935..1300350 (-) 1416 WP_096811580.1 DUF2142 domain-containing protein -
  H0506_RS06720 (STHERMO_1489) - 1300684..1301019 (-) 336 WP_002891474.1 metal-sulfur cluster assembly factor -
  H0506_RS06725 (STHERMO_1490) rpoD 1301073..1302182 (-) 1110 WP_011226338.1 RNA polymerase sigma factor RpoD -
  H0506_RS06730 (STHERMO_1491) dnaG 1302186..1303997 (-) 1812 WP_011226339.1 DNA primase -
  H0506_RS06735 (STHERMO_1492) rpsU 1304368..1304544 (-) 177 WP_011226340.1 30S ribosomal protein S21 -
  H0506_RS06740 (STHERMO_1493) - 1304739..1305533 (-) 795 WP_011226341.1 transporter substrate-binding domain-containing protein -
  H0506_RS06745 (STHERMO_1494) - 1305626..1306735 (-) 1110 WP_041828295.1 aminotransferase -
  H0506_RS06750 (STHERMO_1495) - 1307082..1307879 (-) 798 WP_011226343.1 transporter substrate-binding domain-containing protein -
  H0506_RS06755 (STHERMO_1496) - 1307876..1308706 (-) 831 WP_041828297.1 transporter substrate-binding domain-containing protein -
  H0506_RS06760 (STHERMO_1497) - 1308919..1309383 (-) 465 WP_011226345.1 8-oxo-dGTP diphosphatase -
  H0506_RS06765 (STHERMO_1498) uvrB 1309428..1311419 (-) 1992 WP_002953358.1 excinuclease ABC subunit UvrB -
  H0506_RS09990 - 1312106..1313042 (-) 937 Protein_1272 CPBP family intramembrane glutamic endopeptidase -
  H0506_RS06775 (STHERMO_1504) - 1313241..1315474 (+) 2234 Protein_1273 ABC transporter substrate-binding protein/permease -
  H0506_RS06780 (STHERMO_1505) - 1315474..1316214 (+) 741 WP_002945131.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 71975.95 Da        Isoelectric Point: 5.1750

>NTDB_id=1130921 H0506_RS06565 WP_179971679.1 1269856..1271823(-) (amiA3) [Streptococcus thermophilus isolate STH_CIRM_65]
MKKSKWLALAGVALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDEYTLQYTLKQPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIYYTAPGASTSAIGINLDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLAVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNF
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVDQSSKLNVAQAQSLKQTIEKSLGSENVVIDINQLSSDDLEN
VTLNAANAAAEDWDISNSVAWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPAISRLTPFTGASLQVGDKGSSYVKYVKSQEKVVTKKEYEQSREKWLKEKK
ESNEKAQKDLEKHVK

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=1130921 H0506_RS06565 WP_179971679.1 1269856..1271823(-) (amiA3) [Streptococcus thermophilus isolate STH_CIRM_65]
ATGAAAAAAAGCAAATGGTTGGCTCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTATGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGAGTATACTTTGCAGTACACGCTTAAGCAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAAGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATTAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACGAGTTCAAACTATGCTTCTGTAGAGAAGAAATATAAAGATAATATTTATT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATCTTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGCTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATTTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTGACCAAAGCTCTAAACTTAATGTTGCCCAAGCCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GTAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGCTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCCTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGCTATCTCACGCTTGACACCGTTTACCGGTGCTAGCCTCCAGGTGGGTGATAAGGGCTCATCCTACGTCA
AATATGTGAAATCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAAAAGAAA
GAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(75-520)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA3 Streptococcus thermophilus LMG 18311

99.239

100

0.995
  amiA3 Streptococcus thermophilus LMD-9

97.717

100

0.98
  amiA Streptococcus salivarius strain HSISS4

90.244

100

0.904

Multiple sequence alignment