Detailed information NTG1130579

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H0503_RS08675
• Genome accession: NZ_LR822009
• Coordinates: 1674319..1674756 (-)
• Length: 145 a.a.
• NCBI ID: WP_082309153.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_19
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1669319..1679756

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0503_RS08640 (STHERMO_1945)	-	1669384..1670046 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
H0503_RS08645 (STHERMO_1946)	-	1670143..1670586 (-)	444	WP_084829882.1	CAAX protease	-
H0503_RS10080 (STHERMO_1947)	-	1670660..1671085 (-)	426	WP_087010196.1	CPBP family intramembrane glutamic endopeptidase	-
H0503_RS08655 (STHERMO_1949)	-	1671328..1671525 (-)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
H0503_RS08660 (STHERMO_1950)	-	1671774..1672967 (-)	1194	WP_084831204.1	acetate kinase	-
H0503_RS08665 (STHERMO_1951)	comYH	1673023..1673979 (-)	957	WP_084831205.1	class I SAM-dependent methyltransferase	Machinery gene
H0503_RS08670 (STHERMO_1952)	comGG	1674024..1674341 (-)	318	WP_082309152.1	competence type IV pilus minor pilin ComGG	-
H0503_RS08675 (STHERMO_1953)	comYF	1674319..1674756 (-)	438	WP_082309153.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0503_RS08680 (STHERMO_1954)	comGE	1674740..1675033 (-)	294	WP_082309154.1	competence type IV pilus minor pilin ComGE	-
H0503_RS08685 (STHERMO_1955)	comGD	1675005..1675433 (-)	429	WP_253269448.1	competence type IV pilus minor pilin ComGD	-
H0503_RS08690 (STHERMO_1956)	comYC	1675393..1675719 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H0503_RS08695 (STHERMO_1957)	comYB	1675716..1676816 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0503_RS08700 (STHERMO_1958)	comGA/cglA/cilD	1676698..1677639 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
H0503_RS08705 (STHERMO_1959)	-	1677720..1678082 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16423.93 Da
• Isoelectric Point: 8.9531

>NTDB_id=1130579 H0503_RS08675 WP_082309153.1 1674319..1674756(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_19]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQYLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1130579 H0503_RS08675 WP_082309153.1 1674319..1674756(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTTAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAATACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434