Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   H1D08_RS19130 Genome accession   NZ_LR778146
Coordinates   3946520..3947644 (+) Length   374 a.a.
NCBI ID   WP_097448353.1    Uniprot ID   -
Organism   Escherichia coli isolate SC455     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3941520..3952644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1D08_RS19105 mscL 3941637..3942050 (-) 414 WP_000022450.1 large-conductance mechanosensitive channel protein MscL -
  H1D08_RS19110 trkA 3942180..3943556 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  H1D08_RS19115 rsmB 3943578..3944867 (-) 1290 WP_000744767.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  H1D08_RS19120 fmt 3944919..3945866 (-) 948 WP_097448354.1 methionyl-tRNA formyltransferase -
  H1D08_RS19125 def 3945881..3946390 (-) 510 WP_000114984.1 peptide deformylase -
  H1D08_RS19130 dprA 3946520..3947644 (+) 1125 WP_097448353.1 DNA-protecting protein DprA Machinery gene
  H1D08_RS19135 smg 3947616..3948089 (+) 474 WP_000460673.1 DUF494 family protein Smg -
  H1D08_RS19140 yrdD 3948118..3948660 (+) 543 WP_001312137.1 type I DNA topoisomerase -
  H1D08_RS19145 tsaC 3948665..3949237 (+) 573 WP_001296460.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  H1D08_RS19150 aroE 3949242..3950060 (+) 819 WP_175058681.1 shikimate dehydrogenase -
  H1D08_RS19155 yrdB 3950057..3950314 (+) 258 WP_001070581.1 DUF1488 domain-containing protein -
  H1D08_RS19160 yrdA 3950290..3950844 (-) 555 WP_140426443.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40880.83 Da        Isoelectric Point: 6.0395

>NTDB_id=1130062 H1D08_RS19130 WP_097448353.1 3946520..3947644(+) (dprA) [Escherichia coli isolate SC455]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVAQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=1130062 H1D08_RS19130 WP_097448353.1 3946520..3947644(+) (dprA) [Escherichia coli isolate SC455]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTGT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTTGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCCGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTGCTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (DprA_WH)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39

Multiple sequence alignment