Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   GPW69_RS07985 Genome accession   NZ_LR738724
Coordinates   1642054..1642698 (+) Length   214 a.a.
NCBI ID   WP_002942854.1    Uniprot ID   A0A0M9FM24
Organism   Streptococcus suis isolate 9401240     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1637054..1647698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS07960 - 1637713..1639050 (-) 1338 WP_044762074.1 hemolysin family protein -
  GPW69_RS07965 - 1639183..1639962 (+) 780 WP_074391752.1 ABC transporter ATP-binding protein -
  GPW69_RS07970 - 1639978..1640532 (-) 555 WP_074391751.1 tRNA (mnm(5)s(2)U34)-methyltransferase -
  GPW69_RS07975 - 1640542..1641060 (-) 519 WP_074391750.1 TetR/AcrR family transcriptional regulator -
  GPW69_RS07980 - 1641182..1642000 (+) 819 WP_074391749.1 cation diffusion facilitator family transporter -
  GPW69_RS07985 cclA/cilC 1642054..1642698 (+) 645 WP_002942854.1 prepilin peptidase Machinery gene
  GPW69_RS07990 - 1642806..1644266 (+) 1461 WP_044684097.1 nicotinate phosphoribosyltransferase -
  GPW69_RS07995 nadE 1644279..1645103 (+) 825 WP_044681117.1 ammonia-dependent NAD(+) synthetase -
  GPW69_RS08000 trpB 1645144..1646319 (-) 1176 WP_024406670.1 tryptophan synthase subunit beta -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24144.21 Da        Isoelectric Point: 8.4760

>NTDB_id=1129609 GPW69_RS07985 WP_002942854.1 1642054..1642698(+) (cclA/cilC) [Streptococcus suis isolate 9401240]
MKTIILFFLGASIGSFLGLVIDRFPEQSIISPSSHCNACKRRLKAWDLIPILSQLSTKSKCRYCKAKIPYWYLGLEVLAG
LVVLLCHFQVLNLTETILSLAGLVLTIYDIKHQEYPFAVWLVFTFIALVLSQLNWLFCGFLLLAYLTEKWQVSIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFTIFKPKSIPYVPLLFLSSIPIILCI

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1129609 GPW69_RS07985 WP_002942854.1 1642054..1642698(+) (cclA/cilC) [Streptococcus suis isolate 9401240]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCTCCCCCTCCAGTCACTGCAATGCCTGCAAGCGACGACTCAAGGCCTGGGACCTAATACCCATCCTGTCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGACTAGAAGTCTTAGCTGGT
CTAGTCGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCAGCTTAGCAGGGCTAGTTTTAACCAT
TTACGACATCAAGCATCAGGAATATCCTTTTGCTGTCTGGCTCGTTTTTACTTTTATAGCTCTGGTACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAGTCAGTATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCACTATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTTTTTCTTTCAAGTATTCCTATCATTCTGTGCA
TCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FM24

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.528

99.065

0.491
  cclA/cilC Streptococcus pneumoniae Rx1

48.113

99.065

0.477
  cclA/cilC Streptococcus pneumoniae D39

48.113

99.065

0.477
  cclA/cilC Streptococcus pneumoniae R6

48.113

99.065

0.477
  cclA/cilC Streptococcus pneumoniae TIGR4

47.17

99.065

0.467
  cclA/cilC Streptococcus mitis NCTC 12261

45.283

99.065

0.449

Multiple sequence alignment