Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   GPW68_RS08615 Genome accession   NZ_LR738723
Coordinates   1719446..1720090 (+) Length   214 a.a.
NCBI ID   WP_012027589.1    Uniprot ID   A0A0M9FEX3
Organism   Streptococcus suis isolate GD-0088     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1714446..1725090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS08595 pflA 1715593..1716384 (-) 792 WP_012027587.1 pyruvate formate-lyase-activating protein -
  GPW68_RS08600 - 1716505..1717842 (-) 1338 WP_074389443.1 hemolysin family protein -
  GPW68_RS08605 - 1717975..1718754 (+) 780 WP_012027588.1 ABC transporter ATP-binding protein -
  GPW68_RS08610 - 1718770..1719324 (-) 555 WP_004194627.1 tRNA (mnm(5)s(2)U34)-methyltransferase -
  GPW68_RS08615 cclA/cilC 1719446..1720090 (+) 645 WP_012027589.1 prepilin peptidase Machinery gene
  GPW68_RS08620 - 1720198..1721658 (+) 1461 WP_012027590.1 nicotinate phosphoribosyltransferase -
  GPW68_RS08625 nadE 1721671..1722495 (+) 825 WP_004194617.1 ammonia-dependent NAD(+) synthetase -
  GPW68_RS08635 - 1723736..1724263 (-) 528 WP_012027591.1 VanZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24215.33 Da        Isoelectric Point: 8.4760

>NTDB_id=1129560 GPW68_RS08615 WP_012027589.1 1719446..1720090(+) (cclA/cilC) [Streptococcus suis isolate GD-0088]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALILSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCT

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1129560 GPW68_RS08615 WP_012027589.1 1719446..1720090(+) (cclA/cilC) [Streptococcus suis isolate GD-0088]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCCTCTAGTCACTGCAATGCCTGCAAACGACGGCTCAAGGCCTGGGACTTAATTCCAGTCCTATCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGATTGGAATTCTTAGCCGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAGCATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATAGCTCTGATACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTATTTCTTTCAAGTATTCCTATCATTCTGTGCA
CCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FEX3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.528

99.065

0.491
  cclA/cilC Streptococcus pneumoniae Rx1

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae D39

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae R6

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae TIGR4

47.17

99.065

0.467
  cclA/cilC Streptococcus mitis NCTC 12261

45.755

99.065

0.453

Multiple sequence alignment