Detailed information NTG1129520

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GPW68_RS00330
• Genome accession: NZ_LR738723
• Coordinates: 55420..56319 (+)
• Length: 299 a.a.
• NCBI ID: WP_074389013.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate GD-0088
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	56945..57736	55420..56319	flank	626

Gene organization within MGE regions

Location: 55420..57736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW68_RS00330	comR	55420..56319 (+)	900	WP_074389013.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35432.37 Da
• Isoelectric Point: 4.6995

>NTDB_id=1129520 GPW68_RS00330 WP_074389013.1 55420..56319(+) (comR) [Streptococcus suis isolate GD-0088]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQSK
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide

• Length: 900 bp

>NTDB_id=1129520 GPW68_RS00330 WP_074389013.1 55420..56319(+) (comR) [Streptococcus suis isolate GD-0088]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGTG
TAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGAAA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-294)

• Helix-turn-helix domain (HTH_31) (5-60)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	99.666	100	0.997
comR	Streptococcus suis 05ZYH33	99.666	100	0.997
comR	Streptococcus suis D9	62.126	100	0.625
comR	Streptococcus mutans UA159	43.478	100	0.435
comR	Streptococcus pyogenes MGAS315	37.374	99.331	0.371