Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   GPW48_RS02210 Genome accession   NZ_LR738720
Coordinates   417696..418340 (-) Length   214 a.a.
NCBI ID   WP_012027589.1    Uniprot ID   A0A0M9FEX3
Organism   Streptococcus suis isolate GD-0001     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 412696..423340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS02190 - 413468..413995 (+) 528 WP_012027591.1 VanZ family protein -
  GPW48_RS02200 nadE 415291..416115 (-) 825 WP_004194617.1 ammonia-dependent NAD(+) synthetase -
  GPW48_RS02205 - 416128..417588 (-) 1461 WP_074390043.1 nicotinate phosphoribosyltransferase -
  GPW48_RS02210 cclA/cilC 417696..418340 (-) 645 WP_012027589.1 prepilin peptidase Machinery gene
  GPW48_RS02215 - 418462..419016 (+) 555 WP_004194627.1 tRNA (mnm(5)s(2)U34)-methyltransferase -
  GPW48_RS02220 - 419032..419811 (-) 780 WP_012027588.1 ABC transporter ATP-binding protein -
  GPW48_RS02225 - 419944..421281 (+) 1338 WP_004194632.1 hemolysin family protein -
  GPW48_RS02230 pflA 421402..422193 (+) 792 WP_012027587.1 pyruvate formate-lyase-activating protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24215.33 Da        Isoelectric Point: 8.4760

>NTDB_id=1129388 GPW48_RS02210 WP_012027589.1 417696..418340(-) (cclA/cilC) [Streptococcus suis isolate GD-0001]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALILSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCT

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1129388 GPW48_RS02210 WP_012027589.1 417696..418340(-) (cclA/cilC) [Streptococcus suis isolate GD-0001]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCCTCTAGTCACTGCAATGCCTGCAAACGACGGCTCAAGGCCTGGGACTTAATTCCAGTCCTATCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGATTGGAATTCTTAGCCGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAGCATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATAGCTCTGATACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTATTTCTTTCAAGTATTCCTATCATTCTGTGCA
CCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FEX3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.528

99.065

0.491
  cclA/cilC Streptococcus pneumoniae Rx1

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae D39

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae R6

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae TIGR4

47.17

99.065

0.467
  cclA/cilC Streptococcus mitis NCTC 12261

45.755

99.065

0.453

Multiple sequence alignment