Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FQT45_RS07850 Genome accession   NZ_LR595858
Coordinates   1608408..1609094 (-) Length   228 a.a.
NCBI ID   WP_003082738.1    Uniprot ID   A0A4V0H8F5
Organism   Streptococcus pseudoporcinus strain NCTC10228     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1603408..1614094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT45_RS07830 (NCTC10228_01612) dnaI 1604151..1605053 (-) 903 WP_077322463.1 primosomal protein DnaI -
  FQT45_RS07835 (NCTC10228_01613) - 1605054..1606241 (-) 1188 WP_077322465.1 DnaD domain protein -
  FQT45_RS07840 (NCTC10228_01614) nrdR 1606228..1606722 (-) 495 WP_007894853.1 transcriptional regulator NrdR -
  FQT45_RS07845 (NCTC10228_01615) - 1606917..1608398 (-) 1482 WP_077353827.1 HAMP domain-containing histidine kinase -
  FQT45_RS07850 (NCTC10228_01616) covR 1608408..1609094 (-) 687 WP_003082738.1 two-component system response regulator CovR Regulator
  FQT45_RS07855 (NCTC10228_01617) - 1609313..1609846 (-) 534 WP_077322469.1 YceD family protein -
  FQT45_RS07860 (NCTC10228_01618) htpX 1610042..1610938 (-) 897 WP_077322471.1 zinc metalloprotease HtpX -
  FQT45_RS07865 (NCTC10228_01619) - 1610972..1611526 (-) 555 WP_077322473.1 LemA family protein -
  FQT45_RS07870 (NCTC10228_01620) rsmG 1611676..1612389 (+) 714 WP_077322475.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FQT45_RS07875 (NCTC10228_01621) ktrB 1612474..1613850 (+) 1377 WP_077322477.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26623.61 Da        Isoelectric Point: 4.6541

>NTDB_id=1128492 FQT45_RS07850 WP_003082738.1 1608408..1609094(-) (covR) [Streptococcus pseudoporcinus strain NCTC10228]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1128492 FQT45_RS07850 WP_003082738.1 1608408..1609094(-) (covR) [Streptococcus pseudoporcinus strain NCTC10228]
ATGACAAAGAAAATTCTAATTGTCGAAGATGAAAAAAATCTCGCACGGTTTGTTTCACTTGAACTTCAACATGAAGGGTA
CGAGGTGACAGTAGAAGTAAACGGGCGTGAAGGCCTAGAAACAGCATTAGAAAAAGATTTTGATTTAATTTTACTAGATT
TAATGCTCCCTGAAATGGACGGTTTTGAAGTCACTCGTCGTCTTCAAACTGAGAAAACTACCTATATTATGATGATGACT
GCACGTGATTCTATTATGGACGTTGTAGCAGGTCTTGATCGTGGTGCAGATGATTATATTGTCAAACCATTTGCTATTGA
AGAGTTATTAGCGCGTATTCGGGCAATTTTCCGTCGTCAAGACATTGAAACTGAAAAGAAAGCGCCTAATCAAGGTGTTT
ATCGCGATCTTGTTTTGAACCCTCAAAACAGATCTGTGAACCGTGGTGATGATGAAATTTCATTAACAAAGCGTGAGTAT
GATCTCTTAAATATCCTTATGACAAATATGAATCGTGTAATGACCCGCGAAGAGTTGCTTTCTAATGTCTGGAAATACGA
TGAAGCCGTTGAAACAAATGTTGTTGATGTCTACATTCGTTATCTTCGTGGCAAAATTGACATGCCTGGTCGTGAATCCT
ATATTCAGACTGTTCGTGGCATGGGTTATGTTATCCGTGAAAAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H8F5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.969

100

0.833
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.434

Multiple sequence alignment