Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   FJH52_RS10655 Genome accession   NZ_LR595848
Coordinates   2117631..2118293 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 4559 isolate 4559     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2112631..2123293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FJH52_RS10630 - 2112781..2113047 (-) 267 WP_001278167.1 Veg family protein -
  FJH52_RS10635 dnaB 2113049..2114401 (-) 1353 WP_000852486.1 replicative DNA helicase -
  FJH52_RS10640 rplI 2114445..2114897 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  FJH52_RS10645 - 2114894..2116867 (-) 1974 WP_000715131.1 DHH family phosphoesterase -
  FJH52_RS10650 hpf 2117003..2117551 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  FJH52_RS10655 comFC/cflB 2117631..2118293 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  FJH52_RS10660 comFA/cflA 2118290..2119588 (-) 1299 WP_000867615.1 DEAD/DEAH box helicase Machinery gene
  FJH52_RS10665 - 2119644..2120279 (+) 636 WP_000395739.1 YigZ family protein -
  FJH52_RS10670 cysK 2120564..2121484 (+) 921 WP_000029866.1 cysteine synthase A -
  FJH52_RS10675 - 2121559..2122097 (-) 539 Protein_2089 transposase -
  FJH52_RS10680 - 2122070..2122378 (+) 309 Protein_2090 transposase -
  FJH52_RS10685 tnpB 2122519..2122842 (-) 324 WP_000973416.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=1128369 FJH52_RS10655 WP_000649971.1 2117631..2118293(-) (comFC/cflB) [Streptococcus pneumoniae strain 4559 isolate 4559]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1128369 FJH52_RS10655 WP_000649971.1 2117631..2118293(-) (comFC/cflB) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment