Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   FJH52_RS08545 Genome accession   NZ_LR595848
Coordinates   1719546..1720205 (+) Length   219 a.a.
NCBI ID   WP_000565010.1    Uniprot ID   A0A0B7M2C6
Organism   Streptococcus pneumoniae strain 4559 isolate 4559     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1714546..1725205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FJH52_RS08520 - 1714851..1715168 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  FJH52_RS08525 - 1715183..1716079 (-) 897 WP_000825669.1 PEP phosphonomutase -
  FJH52_RS08530 - 1716082..1717344 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  FJH52_RS08535 - 1717624..1718802 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  FJH52_RS08540 - 1719078..1719476 (-) 399 WP_000155403.1 N-acetyltransferase -
  FJH52_RS08545 cclA/cilC 1719546..1720205 (+) 660 WP_000565010.1 A24 family peptidase Machinery gene
  FJH52_RS08550 - 1720257..1721408 (-) 1152 WP_000481751.1 ImmA/IrrE family metallo-endopeptidase -
  FJH52_RS08555 - 1721423..1722154 (-) 732 Protein_1711 hypothetical protein -
  FJH52_RS08565 - 1722374..1722484 (+) 111 Protein_1712 prepilin peptidase -
  FJH52_RS08570 trpA 1722456..1723232 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  FJH52_RS08575 trpB 1723225..1724448 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  FJH52_RS08580 - 1724426..1725025 (-) 600 WP_000169909.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24845.99 Da        Isoelectric Point: 7.5762

>NTDB_id=1128338 FJH52_RS08545 WP_000565010.1 1719546..1720205(+) (cclA/cilC) [Streptococcus pneumoniae strain 4559 isolate 4559]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1128338 FJH52_RS08545 WP_000565010.1 1719546..1720205(+) (cclA/cilC) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M2C6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

100

100

1
  cclA/cilC Streptococcus pneumoniae D39

100

100

1
  cclA/cilC Streptococcus pneumoniae R6

100

100

1
  cclA/cilC Streptococcus pneumoniae TIGR4

94.977

100

0.95
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment