Detailed information NTG1127974

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FGL23_RS07910
• Genome accession: NZ_LR594049
• Coordinates: 1642274..1644514 (-)
• Length: 746 a.a.
• NCBI ID: WP_061603130.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC10231
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1637274..1649514

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL23_RS07880 (NCTC10231_01571)	-	1637546..1638043 (-)	498	WP_045635087.1	DUF1648 domain-containing protein	-
FGL23_RS07885 (NCTC10231_01572)	-	1638030..1638311 (-)	282	WP_012130660.1	autorepressor SdpR family transcription factor	-
FGL23_RS07890 (NCTC10231_01573)	-	1638289..1639077 (-)	789	WP_061603132.1	YhfC family intramembrane metalloprotease	-
FGL23_RS07895 (NCTC10231_01574)	-	1639283..1640356 (-)	1074	WP_138115456.1	serine hydrolase	-
FGL23_RS07900 (NCTC10231_01575)	sodA	1640468..1641073 (-)	606	WP_045635085.1	superoxide dismutase SodA	-
FGL23_RS07905 (NCTC10231_01576)	holA	1641146..1642183 (-)	1038	WP_061603131.1	DNA polymerase III subunit delta	-
FGL23_RS07910 (NCTC10231_01577)	comEC/celB	1642274..1644514 (-)	2241	WP_061603130.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FGL23_RS07915 (NCTC10231_01578)	comEA/celA/cilE	1644498..1645163 (-)	666	WP_060554135.1	helix-hairpin-helix domain-containing protein	Machinery gene
FGL23_RS07920 (NCTC10231_01579)	-	1645260..1645787 (-)	528	WP_060554134.1	HXXEE domain-containing protein	-
FGL23_RS07925 (NCTC10231_01580)	-	1645826..1646566 (-)	741	WP_060554133.1	lysophospholipid acyltransferase family protein	-
FGL23_RS07930 (NCTC10231_01581)	-	1646696..1649065 (+)	2370	WP_060554132.1	cation-translocating P-type ATPase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85074.98 Da
• Isoelectric Point: 9.8605

>NTDB_id=1127974 FGL23_RS07910 WP_061603130.1 1642274..1644514(-) (comEC/celB) [Streptococcus gordonii strain NCTC10231]
MSQWIKKLPLSPIYLCFLLVWLYFAIYSGEKLAYLGVFLLIARLIWHYPRKKWLPTLAILACFAIFFYARRELTERTFQS
QPAPARQVLVLPDTIKVNGDSLSFRGRIAGRLYQLYYKLASPREKKTFQKLTDLVTLEIEAEFNLAEGQRNFSGFDYQAY
LKSQGIYRTVKVSGIISSRSSQSANPFDWLSVWRRKALVFIKSTFPSPMSHYMTGLLFGDLDIDFAEMNDLYSSLGIIHL
FALSGMQVGFFMDVFRKILLRIGLRMETVDWLQFPLSFIYAGLTGFSVSVVRSLVQKLLSQFGVRRLDNFAMTMLVLMLL
MPSFLLTTGGVLSCAYAFIITMLDFKDSSGFRKAVLESLSISLGILPILIYYFAEFQPWSILLTFLFSIVFDVFMLPLLS
LIFVLSPLFAIIQVNIFFQWLEIVIRWVAGLSTRPIVLGQPNLTLLILLLLALALLYDFRKQKKIKAGLSLLAILLFFLS
KYPLQNEITVVDIGQGDSIFLRDIRGRTIVIDTGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDHLDQLVLTHTDT
DHMGDMLDLAKHFSIREIYVSKGSMTQSDFVGKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLTQGDGGNDDSIVLYGEF
FRTKFLFTGDLEAPGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHQETLERFEKIQ
TKILRTDEQGAIRFKGWSSWKIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1127974 FGL23_RS07910 WP_061603130.1 1642274..1644514(-) (comEC/celB) [Streptococcus gordonii strain NCTC10231]
ATGTCACAGTGGATTAAAAAACTTCCCCTTTCACCAATCTATTTGTGCTTTCTTTTGGTTTGGCTTTACTTCGCTATTTA
TAGTGGGGAAAAGCTCGCTTATCTGGGAGTTTTTCTGCTTATAGCTCGCCTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTTTGGCTATCCTAGCCTGTTTTGCTATCTTTTTTTATGCTAGACGCGAGTTGACGGAGCGAACCTTTCAGTCT
CAACCAGCTCCAGCAAGACAAGTCTTAGTTTTACCAGATACAATTAAAGTAAATGGAGACTCCCTGTCATTCCGTGGTAG
AATAGCTGGCAGACTCTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAAAAACTTTTCAAAAACTAACTGACT
TGGTCACTTTAGAGATAGAAGCGGAGTTCAATCTAGCAGAAGGACAGCGCAATTTCTCTGGCTTTGACTATCAGGCTTAT
TTAAAAAGTCAGGGAATCTATCGGACGGTTAAGGTCAGTGGGATTATCTCTAGTCGTTCTAGTCAGTCTGCTAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCCTTGGTTTTCATTAAGTCTACTTTTCCAAGCCCGATGAGTCACTACATGA
CAGGACTCTTGTTTGGTGATTTAGATATTGATTTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAAGTTGGCTTTTTTATGGATGTCTTTCGAAAAATTCTTCTACGCATTGGCTTAAGAATGGA
AACAGTAGATTGGTTGCAATTCCCTTTGTCCTTTATTTATGCTGGTTTGACCGGATTTTCTGTGTCAGTAGTGAGAAGTT
TAGTGCAAAAGTTGTTGTCTCAATTTGGAGTGAGGCGCTTGGATAATTTTGCGATGACCATGCTGGTCTTAATGCTTCTT
ATGCCAAGCTTTCTCCTGACAACAGGCGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACGATGTTGGACTTTAAAGA
TTCTAGTGGTTTTCGCAAAGCAGTGCTAGAGAGTTTAAGCATCTCGCTAGGTATTTTACCAATTCTTATCTATTATTTTG
CAGAATTCCAGCCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTTTTTGATGTATTTATGTTGCCTCTCTTGAGT
CTAATTTTTGTCCTTTCGCCTTTGTTTGCCATCATTCAAGTTAATATCTTTTTCCAATGGCTGGAAATAGTTATACGTTG
GGTAGCTGGTCTGTCAACAAGGCCAATAGTTTTAGGTCAGCCCAATCTGACTTTGCTTATTCTTCTTCTACTAGCTTTAG
CCTTACTCTATGATTTTAGAAAACAAAAAAAGATTAAGGCTGGTCTGAGTCTGTTAGCAATCTTGCTATTTTTCCTAAGT
AAATATCCCTTGCAAAATGAAATCACAGTGGTTGATATTGGACAAGGAGATAGTATATTTCTGAGAGATATCAGAGGCCG
AACCATTGTAATTGATACAGGAGGACGGGTGGAGATTGGTAAAAAAGAGGCTTGGCAAGAGCGCGTGAGAAAAAGCAATG
CGGAAACGACCTTAATCCCTTATTTAAAAAGTCGAGGAGTGGATCACTTGGATCAATTAGTCCTGACTCACACAGATACA
GACCATATGGGAGATATGTTGGACTTAGCCAAGCATTTTTCTATCCGAGAAATTTATGTTTCCAAAGGAAGTATGACTCA
GTCTGATTTTGTAGGCAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTAGTCGAGGTGGGAGATCGGCTTCCTATTTTTG
ATTCGGCTCTTGAAGTGCTCTACCCGCTTACTCAAGGAGATGGAGGTAATGATGATTCAATTGTCTTGTATGGTGAATTT
TTCCGGACCAAGTTTCTTTTCACAGGAGATTTAGAAGCTCCAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAATCGCTACCAGCATCCGCATCAGGAAACTTTAGAAAGATTTGAAAAAATCCAG
ACCAAGATTTTACGGACAGATGAGCAGGGTGCTATTCGATTTAAAGGATGGAGTTCTTGGAAGATAGAAACAGTTCGCTA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Domain of unknown function (DUF4131) (DUF4131) (35-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	58.902	100	0.59
comEC/celB	Streptococcus pneumoniae TIGR4	58.099	100	0.582
comEC/celB	Streptococcus mitis NCTC 12261	57.641	100	0.576
comEC/celB	Streptococcus pneumoniae Rx1	57.162	100	0.572
comEC/celB	Streptococcus pneumoniae D39	57.162	100	0.572
comEC/celB	Streptococcus pneumoniae R6	57.162	100	0.572
comEC	Lactococcus lactis subsp. cremoris KW2	50.538	99.732	0.504