Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGL22_RS05690 Genome accession   NZ_LR594048
Coordinates   1118212..1119522 (-) Length   436 a.a.
NCBI ID   WP_012766987.1    Uniprot ID   A0AB38Y432
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1113212..1124522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL22_RS05660 (NCTC11556_01167) - 1113646..1114035 (-) 390 WP_003061899.1 cytidine deaminase -
  FGL22_RS05665 (NCTC11556_01168) deoC 1114022..1114684 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  FGL22_RS05670 (NCTC11556_01169) - 1114700..1115977 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  FGL22_RS05675 (NCTC11556_01170) - 1115964..1116563 (-) 600 WP_037589902.1 class I SAM-dependent methyltransferase -
  FGL22_RS05680 (NCTC11556_01171) coaA 1116832..1117752 (+) 921 WP_003058858.1 type I pantothenate kinase -
  FGL22_RS05685 (NCTC11556_01172) rpsT 1117806..1118054 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  FGL22_RS05690 (NCTC11556_01173) ciaH 1118212..1119522 (-) 1311 WP_012766987.1 HAMP domain-containing sensor histidine kinase Regulator
  FGL22_RS05695 (NCTC11556_01174) ciaR 1119515..1120189 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  FGL22_RS05700 (NCTC11556_01175) - 1120393..1122930 (-) 2538 WP_003061495.1 M1 family metallopeptidase -
  FGL22_RS05705 (NCTC11556_01176) phoU 1123131..1123784 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49917.46 Da        Isoelectric Point: 8.2375

>NTDB_id=1127924 FGL22_RS05690 WP_012766987.1 1118212..1119522(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
MNKLKKEVFSDQYNHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1127924 FGL22_RS05690 WP_012766987.1 1118212..1119522(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACAACCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTTATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATCAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.37

100

0.516
  ciaH Streptococcus pneumoniae D39

51.37

100

0.516
  ciaH Streptococcus pneumoniae R6

51.37

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.37

100

0.516

Multiple sequence alignment