Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FGL22_RS00735 Genome accession   NZ_LR594048
Coordinates   120876..121907 (+) Length   343 a.a.
NCBI ID   WP_050807598.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115876..126907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL22_RS00725 (NCTC11556_00147) - 119553..119918 (+) 366 WP_003055257.1 DUF1033 family protein -
  FGL22_RS00730 (NCTC11556_00148) comGA/cglA 119999..120940 (+) 942 WP_003062163.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL22_RS00735 (NCTC11556_00149) comYB 120876..121907 (+) 1032 WP_050807598.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL22_RS00740 (NCTC11556_00150) comYC 121909..122235 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL22_RS10990 (NCTC11556_00151) comGD 122210..122638 (+) 429 WP_037589807.1 competence type IV pilus minor pilin ComGD -
  FGL22_RS00750 (NCTC11556_00152) comGE 122595..122891 (+) 297 WP_003061797.1 competence type IV pilus minor pilin ComGE -
  FGL22_RS00755 (NCTC11556_00153) comGF 122872..123312 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF -
  FGL22_RS00760 (NCTC11556_00154) comGG 123335..123664 (+) 330 WP_003062466.1 competence type IV pilus minor pilin ComGG -
  FGL22_RS00765 (NCTC11556_00155) comYH 123727..124680 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  FGL22_RS00770 (NCTC11556_00156) - 124739..125935 (+) 1197 WP_003058485.1 acetate kinase -
  FGL22_RS00775 (NCTC11556_00157) - 126241..126447 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38935.31 Da        Isoelectric Point: 9.2055

>NTDB_id=1127893 FGL22_RS00735 WP_050807598.1 120876..121907(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLAEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVIILGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFTHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWTQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1127893 FGL22_RS00735 WP_050807598.1 120876..121907(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGGCTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATAATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTACTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGACTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.545

99.417

0.542
  comYB Streptococcus mutans UA159

53.687

98.834

0.531
  comYB Streptococcus gordonii str. Challis substr. CH1

48.968

98.834

0.484
  comGB/cglB Streptococcus mitis NCTC 12261

46.269

97.668

0.452
  comGB/cglB Streptococcus mitis SK321

45.646

97.085

0.443
  comGB/cglB Streptococcus pneumoniae Rx1

44.144

97.085

0.429
  comGB/cglB Streptococcus pneumoniae D39

44.144

97.085

0.429
  comGB/cglB Streptococcus pneumoniae R6

44.144

97.085

0.429
  comGB/cglB Streptococcus pneumoniae TIGR4

44.144

97.085

0.429
  comGB Lactococcus lactis subsp. cremoris KW2

43.068

98.834

0.426

Multiple sequence alignment