Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGL21_RS02165 Genome accession   NZ_LR594047
Coordinates   394884..395570 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 389884..400570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL21_RS02140 (NCTC11554_00433) ktrB 389991..391367 (-) 1377 WP_012766594.1 potassium uptake transporter channel subunit KtrB -
  FGL21_RS02145 (NCTC11554_00434) rsmG 391451..392164 (-) 714 WP_003058986.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FGL21_RS02150 (NCTC11554_00435) - 392317..392874 (+) 558 WP_003058947.1 LemA family protein -
  FGL21_RS02155 (NCTC11554_00436) htpX 392921..393814 (+) 894 WP_003059035.1 zinc metalloprotease HtpX -
  FGL21_RS02160 (NCTC11554_00437) - 394081..394614 (+) 534 WP_014612038.1 DUF177 domain-containing protein -
  FGL21_RS02165 (NCTC11554_00438) covR 394884..395570 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  FGL21_RS02170 (NCTC11554_00439) - 395576..397075 (+) 1500 WP_003058944.1 HAMP domain-containing histidine kinase -
  FGL21_RS02175 (NCTC11554_00440) nrdR 397281..397775 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  FGL21_RS02180 (NCTC11554_00441) - 397759..398937 (+) 1179 WP_138127973.1 DnaD domain protein -
  FGL21_RS02185 (NCTC11554_00442) dnaI 398938..399840 (+) 903 WP_014612041.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1127847 FGL21_RS02165 WP_003049736.1 394884..395570(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1127847 FGL21_RS02165 WP_003049736.1 394884..395570(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment