Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGL18_RS05670 Genome accession   NZ_LR594046
Coordinates   1167485..1168795 (-) Length   436 a.a.
NCBI ID   WP_138125682.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1162485..1173795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS05640 (NCTC6403_01161) - 1162919..1163308 (-) 390 WP_138125674.1 cytidine deaminase -
  FGL18_RS05645 (NCTC6403_01162) deoC 1163295..1163957 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  FGL18_RS05650 (NCTC6403_01163) - 1163973..1165250 (-) 1278 WP_138125676.1 pyrimidine-nucleoside phosphorylase -
  FGL18_RS05655 (NCTC6403_01164) - 1165237..1165836 (-) 600 WP_138125678.1 class I SAM-dependent methyltransferase -
  FGL18_RS05660 (NCTC6403_01165) coaA 1166105..1167025 (+) 921 WP_138125680.1 type I pantothenate kinase -
  FGL18_RS05665 (NCTC6403_01166) rpsT 1167079..1167327 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  FGL18_RS05670 (NCTC6403_01167) ciaH 1167485..1168795 (-) 1311 WP_138125682.1 HAMP domain-containing sensor histidine kinase Regulator
  FGL18_RS05675 (NCTC6403_01168) ciaR 1168788..1169462 (-) 675 WP_138125684.1 response regulator transcription factor Regulator
  FGL18_RS05680 (NCTC6403_01169) - 1169666..1172203 (-) 2538 WP_138125686.1 M1 family metallopeptidase -
  FGL18_RS05685 (NCTC6403_01170) phoU 1172404..1173057 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49964.57 Da        Isoelectric Point: 8.2375

>NTDB_id=1127805 FGL18_RS05670 WP_138125682.1 1167485..1168795(-) (ciaH) [Streptococcus dysgalactiae strain NCTC6403]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLMNFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLSLAQQIVISLKGSIIVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1127805 FGL18_RS05670 WP_138125682.1 1167485..1168795(-) (ciaH) [Streptococcus dysgalactiae strain NCTC6403]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATATACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGCAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGTACAATTTTGAATTCCTTTGATGCTTTTTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACCACTAGCCTGATGAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGTAGAAAGCCGATTTTGG
AAAGTTACGAAAAACAAAAAATGTTTGTGGAAAATGCCAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCCCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCGAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGACGATGGGATCAACCCTCAGTGGACTGACTTGG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGTCCTTAGCTCAACAAATTGTGATATCACTCAAAGGAAGTATCATCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.581

100

0.587
  ciaH Streptococcus pneumoniae Rx1

51.598

100

0.518
  ciaH Streptococcus pneumoniae D39

51.598

100

0.518
  ciaH Streptococcus pneumoniae R6

51.598

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.598

100

0.518

Multiple sequence alignment