Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FGL18_RS03300 Genome accession   NZ_LR594046
Coordinates   634736..635443 (+) Length   235 a.a.
NCBI ID   WP_138125121.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 629736..640443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS03280 (NCTC6403_00673) ftsY 630297..631847 (+) 1551 WP_138125115.1 signal recognition particle-docking protein FtsY -
  FGL18_RS03285 (NCTC6403_00674) - 631973..632788 (-) 816 WP_003060657.1 TIGR03943 family protein -
  FGL18_RS03290 (NCTC6403_00675) - 632788..633690 (-) 903 WP_138125117.1 permease -
  FGL18_RS10680 (NCTC6403_00676) - 633837..633992 (-) 156 WP_172601425.1 SPJ_0845 family protein -
  FGL18_RS03295 (NCTC6403_00677) - 634173..634649 (+) 477 WP_172601470.1 cupin domain-containing protein -
  FGL18_RS03300 (NCTC6403_00678) vicR 634736..635443 (+) 708 WP_138125121.1 response regulator transcription factor Regulator
  FGL18_RS03305 (NCTC6403_00679) - 635444..636772 (+) 1329 WP_138125123.1 ATP-binding protein -
  FGL18_RS03310 (NCTC6403_00680) - 636939..637814 (+) 876 WP_138125125.1 substrate-binding domain-containing protein -
  FGL18_RS03315 (NCTC6403_00682) pstC 637932..638795 (+) 864 WP_138125127.1 phosphate ABC transporter permease subunit PstC -
  FGL18_RS03320 (NCTC6403_00683) pstA 638788..639603 (+) 816 WP_138125130.1 phosphate ABC transporter permease PstA -
  FGL18_RS03325 (NCTC6403_00684) pstB 639605..640357 (+) 753 WP_138125132.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27473.64 Da        Isoelectric Point: 5.2462

>NTDB_id=1127797 FGL18_RS03300 WP_138125121.1 634736..635443(+) (vicR) [Streptococcus dysgalactiae strain NCTC6403]
MTKQILLVDDEEHILRLLDYHLSKEGFSTQLVTDGRKALTLAETEPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAILRRTSNEQQEDDTDDLRDDYRVFGALTVYPDRHEVYKADHLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDNPKDPQFIQTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1127797 FGL18_RS03300 WP_138125121.1 634736..635443(+) (vicR) [Streptococcus dysgalactiae strain NCTC6403]
ATGACAAAACAAATCTTATTAGTGGATGATGAAGAACACATTTTGAGGCTACTGGATTATCATCTCAGTAAAGAAGGGTT
TTCCACACAATTGGTAACAGATGGCCGAAAAGCATTGACATTGGCAGAAACAGAGCCTTTTGACTTTATCCTATTGGATA
TTATGTTGCCTCAGTTAGACGGCATAGAAGTGTGTAAGCGACTGAGAGCTAAAGGAATAAAAACCCCGATTATGATGGTT
TCTGCTAAAAGTGATGAATTTGATAAGGTTTTGGCCTTAGAATTAGGAGCTGATGATTACCTGACAAAACCTTTCAGCCC
CAGGGAATTGCTGGCGCGTGTCAAGGCTATTTTACGTCGAACCAGTAACGAGCAGCAAGAAGATGACACAGATGATCTCA
GGGATGATTATCGGGTATTTGGGGCCCTGACCGTCTATCCAGACCGGCATGAGGTGTATAAGGCAGATCATTTATTGAGC
CTTACCCCAAAGGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACCTTAACTAGGGAACGTTTACTTGA
ACGGATTTGGGGATATGATTTTGGACAAGAAACCCGTTTAGTGGATGTTCATATTGGCAAATTGAGAGATAAGATAGAGG
ATAACCCTAAAGACCCTCAATTTATTCAAACGATTAGAGGCTATGGGTATAAGTTTAAGGAGTTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

49.573

99.574

0.494
  micA Streptococcus pneumoniae Cp1015

47.619

98.298

0.468
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.202

99.149

0.409
  covR Streptococcus salivarius strain HSISS4

40.171

99.574

0.4

Multiple sequence alignment