Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   LG36_RS11245 Genome accession   NZ_CP009472
Coordinates   2326425..2327018 (-) Length   197 a.a.
NCBI ID   WP_003131995.1    Uniprot ID   Q9CDL2
Organism   Lactococcus lactis strain AI06     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2321425..2332018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LG36_RS12135 (LG36_2139) - 2321426..2321578 (-) 153 WP_173402267.1 hypothetical protein -
  LG36_RS12285 (LG36_2140) - 2321871..2322038 (-) 168 WP_230315131.1 hypothetical protein -
  LG36_RS11885 - 2322320..2322622 (+) 303 Protein_2203 integrase core domain-containing protein -
  LG36_RS11220 (LG36_2141) - 2322866..2323150 (-) 285 WP_038602483.1 bacteriocin immunity protein -
  LG36_RS11950 (LG36_2142) - 2323188..2323361 (-) 174 WP_229049640.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  LG36_RS11225 (LG36_2143) - 2323473..2323793 (-) 321 WP_038602485.1 hypothetical protein -
  LG36_RS11890 (LG36_2144) - 2323928..2324089 (-) 162 WP_118263635.1 bacteriocin -
  LG36_RS11235 (LG36_2145) - 2324275..2325159 (-) 885 WP_038602487.1 XRE/MutR family transcriptional regulator -
  LG36_RS11240 (LG36_2146) ruvB 2325297..2326298 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  LG36_RS11245 (LG36_2147) ruvA 2326425..2327018 (-) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  LG36_RS11250 (LG36_2148) hexB 2327131..2329101 (-) 1971 WP_038602490.1 DNA mismatch repair endonuclease MutL Machinery gene
  LG36_RS11255 (LG36_2149) - 2329230..2329925 (-) 696 WP_038602492.1 hypothetical protein -

Sequence

Protein


Download         Length: 197 a.a.        Molecular weight: 21166.73 Da        Isoelectric Point: 5.8174

>NTDB_id=112779 LG36_RS11245 WP_003131995.1 2326425..2327018(-) (ruvA) [Lactococcus lactis strain AI06]
MFEYLNGKLVKISPTNIVIDVAGIGYLISVANPYAWSALMNTEVKIYVHQVIREDAHSLYGFVNEAEKALFLRLISVSGI
GPKSALAIIAAADNEGLITAIDNSDIKYLTKFPGVGKKTAMQMVLDLAGKFDATGTVGISLLDAGPAGNLALEEAIEALQ
ALGYKATELKKIEKKLAQETGLTSEEYIKSALKLMMK

Nucleotide


Download         Length: 594 bp        

>NTDB_id=112779 LG36_RS11245 WP_003131995.1 2326425..2327018(-) (ruvA) [Lactococcus lactis strain AI06]
ATGTTTGAATATCTTAATGGAAAATTAGTAAAAATTTCCCCAACAAATATTGTAATTGATGTAGCAGGAATTGGCTATCT
TATCAGTGTAGCTAACCCTTACGCTTGGTCGGCTTTGATGAACACAGAAGTAAAAATTTATGTTCATCAAGTCATTCGTG
AAGATGCCCACAGTCTCTATGGTTTTGTTAACGAGGCCGAAAAAGCTTTATTCTTACGTCTGATCAGCGTTTCTGGGATT
GGGCCAAAATCAGCTCTGGCCATCATTGCGGCGGCTGATAACGAAGGTTTAATCACTGCTATTGACAATAGTGATATCAA
GTATTTAACTAAATTCCCAGGAGTTGGTAAAAAAACAGCCATGCAGATGGTGCTTGATTTGGCTGGGAAATTTGATGCGA
CAGGAACTGTAGGTATTTCTCTTCTTGATGCTGGACCTGCTGGCAATCTTGCTTTGGAAGAAGCGATTGAAGCGCTGCAA
GCTTTGGGTTATAAAGCAACAGAATTGAAGAAAATTGAGAAAAAATTAGCTCAAGAAACAGGTCTGACCAGCGAAGAATA
TATCAAATCAGCCTTAAAACTTATGATGAAATAA

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(151-196)

Helix-hairpin-helix domain (HHH_5)

(71-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CDL2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

60.101

100

0.604
  ruvA Streptococcus pneumoniae R6

60.101

100

0.604
  ruvA Streptococcus pneumoniae D39

60.101

100

0.604
  ruvA Bacillus subtilis subsp. subtilis str. 168

44.828

100

0.462

Multiple sequence alignment