Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   LG36_RS11250 Genome accession   NZ_CP009472
Coordinates   2327131..2329101 (-) Length   656 a.a.
NCBI ID   WP_038602490.1    Uniprot ID   -
Organism   Lactococcus lactis strain AI06     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2322131..2334101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LG36_RS11885 - 2322320..2322622 (+) 303 Protein_2203 integrase core domain-containing protein -
  LG36_RS11220 (LG36_2141) - 2322866..2323150 (-) 285 WP_038602483.1 bacteriocin immunity protein -
  LG36_RS11950 (LG36_2142) - 2323188..2323361 (-) 174 WP_229049640.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  LG36_RS11225 (LG36_2143) - 2323473..2323793 (-) 321 WP_038602485.1 hypothetical protein -
  LG36_RS11890 (LG36_2144) - 2323928..2324089 (-) 162 WP_118263635.1 bacteriocin -
  LG36_RS11235 (LG36_2145) - 2324275..2325159 (-) 885 WP_038602487.1 XRE/MutR family transcriptional regulator -
  LG36_RS11240 (LG36_2146) ruvB 2325297..2326298 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  LG36_RS11245 (LG36_2147) ruvA 2326425..2327018 (-) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  LG36_RS11250 (LG36_2148) hexB 2327131..2329101 (-) 1971 WP_038602490.1 DNA mismatch repair endonuclease MutL Machinery gene
  LG36_RS11255 (LG36_2149) - 2329230..2329925 (-) 696 WP_038602492.1 hypothetical protein -
  LG36_RS11260 (LG36_2150) hexA 2330040..2332562 (-) 2523 WP_038602495.1 DNA mismatch repair protein MutS Machinery gene
  LG36_RS11265 (LG36_2151) - 2332756..2333103 (-) 348 WP_012898702.1 RicAFT regulatory complex protein RicA family protein -
  LG36_RS11270 - 2333443..2333643 (-) 201 WP_052053866.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73650.98 Da        Isoelectric Point: 5.2459

>NTDB_id=112780 LG36_RS11250 WP_038602490.1 2327131..2329101(-) (hexB) [Lactococcus lactis strain AI06]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLVAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSLP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKEILSVQTELPLQNNPLYYDNIRQDFYVREEATFKINKNQASNDSTEQTFDNFTE
NQLNTDAVSEKMIDSTVESTTEITDKSLENTVSNFGIDFDNEVKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLAKNDFVVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDGESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=112780 LG36_RS11250 WP_038602490.1 2327131..2329101(-) (hexB) [Lactococcus lactis strain AI06]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTCGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAGTTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GGATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGCTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCTTACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCAATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCATTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
GATTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATATTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAAGCTTCAAATGATTCGACTGAACAAACTTTTGATAATTTTACAGAA
AATCAGCTCAATACTGATGCTGTCAGTGAAAAAATGATTGACAGCACTGTTGAAAGTACTACTGAAATTACTGACAAGAG
TCTAGAAAATACTGTCAGCAACTTTGGAATTGATTTTGATAATGAAGTAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTATTTGGTTGACCAACATGCG
GCTCAAGAGCGAATTAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTAGCCAAAAATGATTTTGTTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACGGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGTAAAAGTTCAATTAAAGCTAATCATCCCCTTGACGGCGAGTCAGCTAGAGCTTTACTCGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(455-598)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-123)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

57.035

100

0.575

Multiple sequence alignment