Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGL18_RS02180 Genome accession   NZ_LR594046
Coordinates   412071..412757 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 407071..417757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS02155 (NCTC6403_00440) ktrB 407180..408556 (-) 1377 WP_012766594.1 potassium uptake transporter channel subunit KtrB -
  FGL18_RS02160 (NCTC6403_00441) rsmG 408640..409353 (-) 714 WP_138124835.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FGL18_RS02165 (NCTC6403_00442) - 409506..410063 (+) 558 WP_138124837.1 LemA family protein -
  FGL18_RS02170 (NCTC6403_00443) htpX 410108..411001 (+) 894 WP_138124839.1 zinc metalloprotease HtpX -
  FGL18_RS02175 (NCTC6403_00444) - 411268..411801 (+) 534 WP_138126948.1 YceD family protein -
  FGL18_RS02180 (NCTC6403_00445) covR 412071..412757 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  FGL18_RS02185 (NCTC6403_00446) - 412763..414262 (+) 1500 WP_138124841.1 HAMP domain-containing histidine kinase -
  FGL18_RS02190 (NCTC6403_00447) nrdR 414469..414963 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  FGL18_RS02195 (NCTC6403_00448) - 414947..416125 (+) 1179 WP_012766597.1 DnaD domain protein -
  FGL18_RS02200 (NCTC6403_00449) dnaI 416126..417028 (+) 903 WP_003058998.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1127788 FGL18_RS02180 WP_003049736.1 412071..412757(+) (covR) [Streptococcus dysgalactiae strain NCTC6403]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1127788 FGL18_RS02180 WP_003049736.1 412071..412757(+) (covR) [Streptococcus dysgalactiae strain NCTC6403]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACCGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment