Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGL14_RS05985 Genome accession   NZ_LR594045
Coordinates   1143201..1144511 (-) Length   436 a.a.
NCBI ID   WP_138083874.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1138201..1149511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL14_RS05955 (NCTC9413_01229) - 1138636..1139025 (-) 390 WP_003058840.1 cytidine deaminase -
  FGL14_RS05960 (NCTC9413_01230) deoC 1139012..1139674 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  FGL14_RS05965 (NCTC9413_01231) - 1139690..1140967 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  FGL14_RS05970 (NCTC9413_01232) - 1140954..1141553 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  FGL14_RS05975 (NCTC9413_01233) coaA 1141821..1142741 (+) 921 WP_048327791.1 type I pantothenate kinase -
  FGL14_RS05980 (NCTC9413_01234) rpsT 1142795..1143043 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  FGL14_RS05985 (NCTC9413_01235) ciaH 1143201..1144511 (-) 1311 WP_138083874.1 HAMP domain-containing sensor histidine kinase Regulator
  FGL14_RS05990 (NCTC9413_01236) ciaR 1144504..1145178 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  FGL14_RS05995 (NCTC9413_01237) - 1145382..1147919 (-) 2538 WP_138083875.1 M1 family metallopeptidase -
  FGL14_RS06000 (NCTC9413_01238) phoU 1148120..1148773 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49964.56 Da        Isoelectric Point: 8.2375

>NTDB_id=1127746 FGL14_RS05985 WP_138083874.1 1143201..1144511(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNFFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1127746 FGL14_RS05985 WP_138083874.1 1143201..1144511(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTTTTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATCAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.142

100

0.514
  ciaH Streptococcus pneumoniae D39

51.142

100

0.514
  ciaH Streptococcus pneumoniae R6

51.142

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.142

100

0.514

Multiple sequence alignment