Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGL06_RS07540 Genome accession   NZ_LR594042
Coordinates   1511567..1512259 (-) Length   230 a.a.
NCBI ID   WP_021143010.1    Uniprot ID   A0A239R7J1
Organism   Streptococcus equinus strain NCTC8133     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1506567..1517259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS07520 (NCTC8133_01525) dnaI 1507375..1508277 (-) 903 WP_094140146.1 primosomal protein DnaI -
  FGL06_RS07525 (NCTC8133_01526) - 1508288..1509439 (-) 1152 WP_126438068.1 DnaD domain protein -
  FGL06_RS07530 (NCTC8133_01527) nrdR 1509426..1509920 (-) 495 WP_004233042.1 transcriptional regulator NrdR -
  FGL06_RS07535 (NCTC8133_01528) - 1510080..1511462 (-) 1383 WP_231997649.1 ATP-binding protein -
  FGL06_RS07540 (NCTC8133_01529) covR 1511567..1512259 (-) 693 WP_021143010.1 response regulator transcription factor Regulator
  FGL06_RS07545 (NCTC8133_01530) - 1512499..1513035 (-) 537 WP_024343625.1 YceD family protein -
  FGL06_RS07550 (NCTC8133_01531) htpX 1513184..1514083 (-) 900 WP_024343624.1 zinc metalloprotease HtpX -
  FGL06_RS07555 (NCTC8133_01532) - 1514200..1514751 (-) 552 WP_021143013.1 LemA family protein -
  FGL06_RS07560 (NCTC8133_01533) rsmG 1515046..1515759 (+) 714 WP_024343622.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FGL06_RS07565 (NCTC8133_01534) - 1515825..1517198 (+) 1374 WP_126438071.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26437.38 Da        Isoelectric Point: 4.8639

>NTDB_id=1127588 FGL06_RS07540 WP_021143010.1 1511567..1512259(-) (covR) [Streptococcus equinus strain NCTC8133]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQEANSKHDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1127588 FGL06_RS07540 WP_021143010.1 1511567..1512259(-) (covR) [Streptococcus equinus strain NCTC8133]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTCGTGTCTTTGGAGTTACAACACGAAGGGTA
TTCAGTAGTTGTTGAGACAAATGGGCGTTTAGGTTTACAAACGGCTTTAGATGATGATTTTGATTTGATCCTGTTGGACT
TGATGTTGCCTGATATGGATGGATTCGAAATTACACGTCGTCTTCGTTTGGAAAAAGAAACTTCAATTATCATGATGACA
GCTCGTGATTCAATCATGGATATCGTTGCTGGTCTTGATCGTGGTGCAGATGATTACATCGTAAAACCATTTGCTATTGA
AGAACTATTAGCGCGTGTGCGTGCAGTGTTCCGTCGTCAAGAAGCTAATTCTAAACATGATAAAGAAGGCCAAGCAAAAG
AGGGGTTGCTAGGACTTCGTCTTAATCCACAAAATCGTTCTGCAGTTCGTGGAGACGATGAAATTTCATTAACAAAACGC
GAATATGATTTGTTAAGTGTTCTTCTTTCAAACGTTAACCGAGTGATGACACGTGAAGAATTACTTGCAAGTGTTTGGCG
TTATGATACTGATATCGAAACAAACGTAGTGGATGTTTACATCCGTTATCTTCGTGGAAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACTGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239R7J1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

41.991

100

0.422
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417

Multiple sequence alignment