Detailed information NTG1127484

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: FGL12_RS03280
• Genome accession: NZ_LR594041
• Coordinates: 692845..693507 (-)
• Length: 220 a.a.
• NCBI ID: WP_012000141.1
• Uniprot ID: A8AW07
• Organism: Streptococcus gordonii strain NCTC9124
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 687845..698507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL12_RS03250 (NCTC9124_00652)	-	687975..688538 (+)	564	WP_012000135.1	aminodeoxychorismate/anthranilate synthase component II	-
FGL12_RS03255 (NCTC9124_00653)	trpD	688549..689553 (+)	1005	WP_012000136.1	anthranilate phosphoribosyltransferase	-
FGL12_RS03260 (NCTC9124_00654)	trpC	689550..690317 (+)	768	WP_012000137.1	indole-3-glycerol phosphate synthase TrpC	-
FGL12_RS03265 (NCTC9124_00655)	-	690304..690891 (+)	588	WP_012000138.1	phosphoribosylanthranilate isomerase	-
FGL12_RS03270 (NCTC9124_00656)	trpB	690881..692104 (+)	1224	WP_012000139.1	tryptophan synthase subunit beta	-
FGL12_RS03275 (NCTC9124_00657)	trpA	692097..692876 (+)	780	WP_012000140.1	tryptophan synthase subunit alpha	-
FGL12_RS03280 (NCTC9124_00658)	cclA/cilC	692845..693507 (-)	663	WP_012000141.1	A24 family peptidase	Machinery gene
FGL12_RS03290 (NCTC9124_00659)	-	693676..694191 (+)	516	WP_008809115.1	Dps family protein	-
FGL12_RS03295 (NCTC9124_00660)	-	694333..694593 (+)	261	WP_012000142.1	YqgQ family protein	-
FGL12_RS03300 (NCTC9124_00661)	-	694590..694967 (+)	378	WP_020992684.1	rhodanese-like domain-containing protein	-
FGL12_RS03305 (NCTC9124_00662)	-	695133..695858 (-)	726	WP_138101153.1	pseudouridine synthase	-
FGL12_RS03310 (NCTC9124_00663)	typA	696040..697887 (+)	1848	WP_012000144.1	translational GTPase TypA	-
FGL12_RS03315 (NCTC9124_00664)	-	697911..698189 (+)	279	WP_012000145.1	DUF3165 family protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 24731.17 Da
• Isoelectric Point: 8.6451

>NTDB_id=1127484 FGL12_RS03280 WP_012000141.1 692845..693507(-) (cclA/cilC) [Streptococcus gordonii strain NCTC9124]
MIHLYFFLVGTVFASFLGLVIDRFPEQSIITPASHCNACGKRLAPRDLIPIVSQVLNRLRCRFCGDKIPLRYLFFECIFG
CLFLATSLGTISISQLLLLTMGITLAIYDQRELQYPLMIWLVFQLLLLMISGINLLILFFLALGLLAFFYNLRIGAGDFL
FLASCSAIFSLTEILILIQIASFSGLACFCFKKKKDRLAFVPCLLFGVVVIISYKLLLLG

Nucleotide

• Length: 663 bp

>NTDB_id=1127484 FGL12_RS03280 WP_012000141.1 692845..693507(-) (cclA/cilC) [Streptococcus gordonii strain NCTC9124]
ATGATTCACCTATACTTTTTTCTTGTTGGTACCGTCTTTGCCTCATTCCTAGGCTTGGTCATCGACCGCTTCCCAGAGCA
GTCTATCATCACACCAGCTAGTCATTGTAATGCCTGTGGGAAAAGACTGGCCCCTCGTGACTTGATTCCTATTGTTTCCC
AAGTCTTGAACCGTCTTCGCTGTCGCTTCTGTGGAGACAAGATTCCCTTACGTTATTTATTTTTTGAATGTATCTTTGGC
TGTCTTTTTCTGGCCACTTCACTTGGTACAATTTCTATCAGTCAACTCCTGCTACTTACCATGGGCATAACGTTGGCCAT
ATATGATCAAAGAGAGCTGCAATACCCCTTAATGATCTGGTTAGTTTTTCAGCTCTTGTTGCTAATGATATCGGGCATCA
ATCTTCTCATACTCTTCTTTTTAGCCCTAGGACTTCTAGCCTTCTTTTATAATCTTCGTATTGGAGCTGGTGACTTTCTT
TTTCTTGCTTCCTGCTCAGCCATTTTTAGTCTGACGGAAATTCTCATTCTTATCCAAATCGCTAGCTTCTCTGGCCTCGC
CTGTTTCTGCTTTAAAAAGAAAAAAGACAGGCTGGCATTTGTACCCTGTCTTTTGTTTGGTGTGGTGGTGATTATTTCTT
ATAAGCTGCTGCTTCTTGGATAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-86)

3D structure

• AlphaFold DB: A8AW07

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	59.361	99.545	0.591
cclA/cilC	Streptococcus mitis SK321	58.904	99.545	0.586
cclA/cilC	Streptococcus pneumoniae Rx1	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae D39	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae R6	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae TIGR4	57.534	99.545	0.573