Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGL04_RS08820 Genome accession   NZ_LR594035
Coordinates   1710379..1711065 (-) Length   228 a.a.
NCBI ID   WP_003082738.1    Uniprot ID   A0A4V0H8F5
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1705379..1716065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS08800 (NCTC5385_01917) dnaI 1706121..1707023 (-) 903 WP_138068924.1 primosomal protein DnaI -
  FGL04_RS08805 (NCTC5385_01918) - 1707024..1708211 (-) 1188 WP_138068925.1 DnaD domain protein -
  FGL04_RS08810 (NCTC5385_01919) nrdR 1708198..1708692 (-) 495 WP_007894853.1 transcriptional regulator NrdR -
  FGL04_RS08815 (NCTC5385_01920) - 1708888..1710369 (-) 1482 WP_138068926.1 HAMP domain-containing sensor histidine kinase -
  FGL04_RS08820 (NCTC5385_01921) covR 1710379..1711065 (-) 687 WP_003082738.1 two-component system response regulator CovR Regulator
  FGL04_RS08825 (NCTC5385_01922) - 1711284..1711817 (-) 534 WP_138069177.1 YceD family protein -
  FGL04_RS08830 (NCTC5385_01923) htpX 1712013..1712909 (-) 897 WP_138068927.1 zinc metalloprotease HtpX -
  FGL04_RS08835 (NCTC5385_01924) - 1712943..1713497 (-) 555 WP_138068928.1 LemA family protein -
  FGL04_RS08840 (NCTC5385_01925) rsmG 1713647..1714360 (+) 714 WP_138068929.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FGL04_RS08845 (NCTC5385_01926) ktrB 1714445..1715821 (+) 1377 WP_138068930.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26623.61 Da        Isoelectric Point: 4.6541

>NTDB_id=1127317 FGL04_RS08820 WP_003082738.1 1710379..1711065(-) (covR) [Streptococcus pseudoporcinus strain NCTC5385]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1127317 FGL04_RS08820 WP_003082738.1 1710379..1711065(-) (covR) [Streptococcus pseudoporcinus strain NCTC5385]
ATGACAAAGAAAATTCTAATTGTTGAAGATGAAAAAAATCTCGCACGGTTTGTTTCACTTGAACTTCAACATGAAGGGTA
CGAGGTGACAGTAGAAGTAAACGGGCGTGAAGGCCTAGAAACAGCATTAGAAAAAGATTTTGATTTAATTTTGCTAGATT
TAATGCTCCCTGAAATGGACGGTTTTGAAGTCACTCGTCGTCTTCAAACTGAGAAAACTACCTATATCATGATGATGACT
GCACGTGATTCTATTATGGACGTTGTAGCAGGTCTTGATCGTGGTGCAGATGATTATATTGTCAAACCATTTGCTATTGA
AGAGTTATTAGCGCGTATTCGGGCGATTTTCCGTCGTCAAGACATTGAAACTGAAAAGAAAGCGCCTAATCAAGGTGTTT
ATCGCGACCTTGTTTTGAACCCTCAAAACAGATCTGTGAACCGTGGTGATGATGAAATTTCATTAACAAAGCGTGAGTAT
GATCTCTTGAATATCCTTATGACAAATATGAATCGTGTAATGACCCGCGAAGAGTTGCTTTCTAATGTTTGGAAATACGA
TGAAGCCGTTGAAACAAATGTTGTTGATGTCTACATTCGTTATCTTCGTGGCAAAATTGACATGCCTGGTCGTGAATCCT
ATATTCAGACTGTTCGTGGCATGGGTTATGTTATCCGTGAAAAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H8F5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.969

100

0.833
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.434

Multiple sequence alignment