Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGK99_RS08350 Genome accession   NZ_LR594033
Coordinates   1750789..1751475 (-) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1745789..1756475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS08330 (NCTC4675_01689) dnaI 1746554..1747462 (-) 909 WP_012516249.1 primosomal protein DnaI -
  FGK99_RS08335 (NCTC4675_01690) - 1747463..1748626 (-) 1164 WP_172453712.1 helicase loader -
  FGK99_RS08340 (NCTC4675_01691) nrdR 1748610..1749104 (-) 495 WP_012516251.1 transcriptional regulator NrdR -
  FGK99_RS08345 (NCTC4675_01692) - 1749295..1750785 (-) 1491 WP_012516252.1 HAMP domain-containing sensor histidine kinase -
  FGK99_RS08350 (NCTC4675_01693) covR 1750789..1751475 (-) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  FGK99_RS08355 (NCTC4675_01694) - 1751660..1752193 (-) 534 WP_012677411.1 YceD family protein -
  FGK99_RS08360 (NCTC4675_01695) htpX 1752481..1753374 (-) 894 WP_014623438.1 zinc metalloprotease HtpX -
  FGK99_RS08365 (NCTC4675_01696) - 1753406..1753963 (-) 558 WP_138119752.1 LemA family protein -
  FGK99_RS08370 (NCTC4675_01697) rsmG 1754099..1754812 (+) 714 WP_014623439.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1127197 FGK99_RS08350 WP_012516253.1 1750789..1751475(-) (covR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1127197 FGK99_RS08350 WP_012516253.1 1750789..1751475(-) (covR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCGCTTGAGCTACAACATGAGGGTTA
CGAGGTGACCGTCGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGATTTGAAGTGACACGTCGCTTGCAAACAGAAAAAACGACTTACATCATGATGATGACT
GCGCGTGACTCTATTATGGACGTTGTAGCCGGCTTGGATCGTGGTGCTGATGATTATATCGTGAAGCCATTTGCCATTGA
GGAATTGCTGGCGCGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAAACTAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATCGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment