Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FGK99_RS06995 Genome accession   NZ_LR594033
Coordinates   1475378..1476730 (-) Length   450 a.a.
NCBI ID   WP_012677636.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1470378..1481730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS06980 (NCTC4675_01417) - 1470679..1472610 (+) 1932 WP_042670951.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  FGK99_RS06985 (NCTC4675_01418) - 1472631..1474373 (-) 1743 WP_043026181.1 restriction endonuclease FokI C-terminal domain-containing protein -
  FGK99_RS06990 (NCTC4675_01419) vicX 1474565..1475374 (-) 810 WP_042357090.1 MBL fold metallo-hydrolase Regulator
  FGK99_RS06995 (NCTC4675_01420) vicK 1475378..1476730 (-) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGK99_RS07000 (NCTC4675_01421) vicR 1476723..1477433 (-) 711 WP_012515994.1 response regulator YycF Regulator
  FGK99_RS07005 (NCTC4675_01422) - 1477642..1478658 (-) 1017 WP_138119569.1 DUF3114 domain-containing protein -
  FGK99_RS07010 (NCTC4675_01423) - 1478703..1479965 (-) 1263 WP_043040863.1 AMP-binding protein -
  FGK99_RS07015 (NCTC4675_01424) - 1479955..1481070 (-) 1116 WP_138119570.1 acetyl-CoA C-acyltransferase -
  FGK99_RS07020 (NCTC4675_01425) - 1481067..1481606 (-) 540 WP_138119571.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51541.94 Da        Isoelectric Point: 5.5557

>NTDB_id=1127186 FGK99_RS06995 WP_012677636.1 1475378..1476730(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1127186 FGK99_RS06995 WP_012677636.1 1475378..1476730(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCATAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAACGACCTATCAGAT
GTTTTTCGTCTGACCCATGAAAACCTTGCCCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACCAGTACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCTGA
TGGTGGGAAAATTATCGTAAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGTTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCGCAGGGGGGTACCGGC
TTAGGGCTGGCTATTGCCAAAGAAATTATCAAGCAGCACCGAGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment