Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   FGK91_RS00330 Genome accession   NZ_LR590483
Coordinates   53224..54135 (+) Length   303 a.a.
NCBI ID   WP_002986681.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8318     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48224..59135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK91_RS00310 (NCTC8318_00062) purE 48508..48999 (+) 492 WP_023079042.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  FGK91_RS00315 (NCTC8318_00063) purK 48986..50059 (+) 1074 WP_023079033.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  FGK91_RS00320 (NCTC8318_00064) - 50086..51783 (+) 1698 WP_020904816.1 AIPR family protein -
  FGK91_RS00325 (NCTC8318_00065) purB 51801..53093 (+) 1293 WP_023079043.1 adenylosuccinate lyase -
  FGK91_RS00330 (NCTC8318_00066) comR 53224..54135 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  FGK91_RS00335 (NCTC8318_00068) ruvB 54361..55359 (+) 999 WP_014407198.1 Holliday junction branch migration DNA helicase RuvB -
  FGK91_RS00340 (NCTC8318_00069) - 55497..55934 (+) 438 WP_023079047.1 low molecular weight protein-tyrosine-phosphatase -
  FGK91_RS00345 (NCTC8318_00070) - 55957..56358 (+) 402 WP_032465955.1 MORN repeat-containing protein -
  FGK91_RS00350 (NCTC8318_00071) - 56355..58130 (+) 1776 WP_023079046.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35757.27 Da        Isoelectric Point: 4.4858

>NTDB_id=1127018 FGK91_RS00330 WP_002986681.1 53224..54135(+) (comR) [Streptococcus pyogenes strain NCTC8318]
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQFELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMA
KIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDVKSY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=1127018 FGK91_RS00330 WP_002986681.1 53224..54135(+) (comR) [Streptococcus pyogenes strain NCTC8318]
ATGTTAGAACATTTTGGTGGAAAAGTAAAAGTGTTAAGACTTGAAAAGAGGATTAGTCGCGAGGACTTGTGTGGGGATGA
GTCTGAACTTTCTGTTCGTCAATTAGCACGGATAGAACTAGGTCAATCCATACCAAGTTTAAGTAAGGTTATTTTTATTG
CAAAAGCCTTAAACGTTAGTGTCGGTTACTTAACTGATGGTGCTGATTTAGAACTACCTAAGCGTTACAAAGAATTAAAA
TACCTTATCTTAAGGACACCAACTTACATGGATGATGGAAAATTACAAGTACGAGAAGAGCAGTTTGATGAAATTTTTGA
GGATTATTATGATAAATTACCAGAGGAAGAGAAAATAATCATTGATTGTTTACAGGCAACTTTAGATACTTTATTGAGTG
AGAATACTAACTTTGGCATTGACTTACTTCAAGAATATTTTAATCAAATAAAGACTAAGGTACGCTTTAGGCAAAATGAT
TTAATACTTCTAGAATTATATTTAGCTTATCTTGATATTGAGGGAATGGATGGACAATATTCAGATAAGATTTTTTATGA
TTCTTTATTAGATAATCTATCAGAACAATTTGAACAATTTGAATTAGATGAATTATTTATAGTTAATAAGATTATCATTG
ATATTTCATCACTAAGCTTAAAAAATAACCGACTTGATAATTTAGAAAAAGCGATTGAAATGAGTCAAAAAATTATGGCG
AAAATTCAAGATTGGAATAGAATGCCTATTTTAAAACTAATAGAATGGAAATATTTTTTAATCAAACAAAAAGATATAAT
AAAAGCAGAACAATCATTTATGAAGGCATGTTTGTTCGCCCAAATGACAGCTGATCAGTATTTGGAAAACAAGTTAATTC
AAGAGTGGGAAAAAGATGTTAAAAGTTATTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

100

100

1
  comR Streptococcus pyogenes MGAS315

58.472

99.34

0.581
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

51.37

96.37

0.495
  comR Streptococcus mutans UA159

46.358

99.67

0.462

Multiple sequence alignment