Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGK94_RS07795 Genome accession   NZ_LR590471
Coordinates   1656549..1657235 (+) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11854     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1651549..1662235
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK94_RS07775 (NCTC11854_01590) rsmG 1653212..1653925 (-) 714 WP_012516257.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FGK94_RS07780 (NCTC11854_01591) - 1654061..1654618 (+) 558 WP_012677410.1 LemA family protein -
  FGK94_RS07785 (NCTC11854_01592) htpX 1654650..1655543 (+) 894 WP_014623438.1 zinc metalloprotease HtpX -
  FGK94_RS07790 (NCTC11854_01593) - 1655831..1656364 (+) 534 WP_012677411.1 YceD family protein -
  FGK94_RS07795 (NCTC11854_01594) covR 1656549..1657235 (+) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  FGK94_RS07800 (NCTC11854_01595) - 1657239..1658729 (+) 1491 WP_012516252.1 HAMP domain-containing sensor histidine kinase -
  FGK94_RS07805 (NCTC11854_01596) nrdR 1658920..1659414 (+) 495 WP_012516251.1 transcriptional regulator NrdR -
  FGK94_RS07810 (NCTC11854_01597) - 1659398..1660561 (+) 1164 WP_195757365.1 helicase loader -
  FGK94_RS07815 (NCTC11854_01598) dnaI 1660562..1661470 (+) 909 WP_042671268.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1126898 FGK94_RS07795 WP_012516253.1 1656549..1657235(+) (covR) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1126898 FGK94_RS07795 WP_012516253.1 1656549..1657235(+) (covR) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCGCTTGAGCTACAACATGAGGGTTA
CGAGGTGACCGTCGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGATTTGAAGTGACACGTCGCTTGCAAACAGAAAAAACGACTTACATCATGATGATGACT
GCGCGTGACTCTATTATGGACGTTGTAGCCGGCTTGGATCGTGGTGCTGATGATTATATCGTGAAGCCATTTGCCATTGA
GGAATTGCTGGCGCGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAAACTAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATCGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment