Detailed information NTG1126588

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: E0F34_RS10150
• Genome accession: NZ_LR536843
• Coordinates: 1873112..1873414 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1868112..1878414

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS10120 (SAMEA104035599_01929)	rnpA	1868799..1869170 (-)	372	WP_000739246.1	ribonuclease P protein component	-
E0F34_RS12195	-	1869187..1869318 (-)	132	WP_000768904.1	hypothetical protein	-
E0F34_RS10125 (SAMEA104035599_01930)	-	1869319..1870509 (-)	1191	WP_000167765.1	acetate kinase	-
E0F34_RS10130 (SAMEA104035599_01931)	comYH	1870560..1871513 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
E0F34_RS10135 (SAMEA104035599_01932)	-	1871574..1872161 (-)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
E0F34_RS10140 (SAMEA104035599_01933)	comGG/cglG	1872264..1872710 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
E0F34_RS10145 (SAMEA104035599_01934)	comGF/cglF	1872688..1873149 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
E0F34_RS10150 (SAMEA104035599_01935)	comGE/cglE	1873112..1873414 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
E0F34_RS10155 (SAMEA104035599_01936)	comGD/cglD	1873377..1873781 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
E0F34_RS10160 (SAMEA104035599_01937)	comGC/cglC	1873774..1874100 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
E0F34_RS10165 (SAMEA104035599_01938)	comGB/cglB	1874102..1875118 (-)	1017	WP_077141332.1	competence type IV pilus assembly protein ComGB	Machinery gene
E0F34_RS10170 (SAMEA104035599_01939)	comGA/cglA/cilD	1875066..1876007 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
E0F34_RS10175 (SAMEA104035599_01940)	-	1876083..1876448 (-)	366	WP_000286415.1	DUF1033 family protein	-
E0F34_RS10180 (SAMEA104035599_01941)	-	1876599..1877657 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=1126588 E0F34_RS10150 WP_000413382.1 1873112..1873414(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=1126588 E0F34_RS10150 WP_000413382.1 1873112..1873414(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4