Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   E0F34_RS00110 Genome accession   NZ_LR536843
Coordinates   19488..19724 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 14488..24724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F34_RS00090 (SAMEA104035599_00018) hpt 15416..15958 (+) 543 WP_000892185.1 hypoxanthine phosphoribosyltransferase -
  E0F34_RS00095 (SAMEA104035599_00019) ftsH 15974..17932 (+) 1959 WP_000744557.1 ATP-dependent zinc metalloprotease FtsH -
  E0F34_RS00100 (SAMEA104035599_00020) - 18038..18391 (+) 354 Protein_19 IS630-like element IS630-Spn1 family transposase -
  E0F34_RS00105 - 18426..19223 (-) 798 Protein_20 transposase -
  E0F34_RS00110 (SAMEA104035599_00021) comW 19488..19724 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  E0F34_RS00115 (SAMEA104035599_00022) - 19955..21241 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  E0F34_RS00120 (SAMEA104035599_00023) tadA 21442..21909 (+) 468 WP_000291874.1 tRNA adenosine(34) deaminase TadA -
  E0F34_RS00130 (SAMEA104035599_00025) - 22096..22539 (+) 444 WP_000701992.1 dUTP diphosphatase -
  E0F34_RS00135 (SAMEA104035599_00026) - 22541..23056 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  E0F34_RS00140 (SAMEA104035599_00027) radA 23070..24431 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=1126531 E0F34_RS00110 WP_000939546.1 19488..19724(+) (comW) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=1126531 E0F34_RS00110 WP_000939546.1 19488..19724(+) (comW) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756


Multiple sequence alignment