Detailed information NTG1126371

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: E0F40_RS10010
• Genome accession: NZ_LR216065
• Coordinates: 1862209..1862511 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1857209..1867511

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F40_RS09980 (SAMEA3714487_01892)	rnpA	1857896..1858267 (-)	372	WP_000739246.1	ribonuclease P protein component	-
E0F40_RS09985 (SAMEA3714487_01893)	-	1858415..1859605 (-)	1191	WP_000167755.1	acetate kinase	-
E0F40_RS09990 (SAMEA3714487_01894)	comYH	1859656..1860609 (-)	954	WP_000345084.1	class I SAM-dependent methyltransferase	Machinery gene
E0F40_RS09995	-	1860670..1861257 (-)	588	Protein_1865	class I SAM-dependent methyltransferase	-
E0F40_RS10000 (SAMEA3714487_01897)	comGG/cglG	1861394..1861807 (-)	414	WP_000265617.1	competence type IV pilus minor pilin ComGG	Machinery gene
E0F40_RS10005 (SAMEA3714487_01898)	comGF/cglF	1861785..1862246 (-)	462	WP_000250529.1	competence type IV pilus minor pilin ComGF	Machinery gene
E0F40_RS10010 (SAMEA3714487_01899)	comGE/cglE	1862209..1862511 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
E0F40_RS10015 (SAMEA3714487_01900)	comGD/cglD	1862474..1862878 (-)	405	WP_000588002.1	competence type IV pilus minor pilin ComGD	Machinery gene
E0F40_RS10020 (SAMEA3714487_01901)	comGC/cglC	1862871..1863137 (-)	267	WP_000962026.1	competence type IV pilus major pilin ComGC	Machinery gene
E0F40_RS10025 (SAMEA3714487_01902)	-	1863139..1863396 (-)	258	WP_000698513.1	hypothetical protein	-
E0F40_RS10030 (SAMEA3714487_01903)	-	1863667..1864623 (-)	957	WP_054385177.1	N-acetylmuramoyl-L-alanine amidase	-
E0F40_RS10035 (SAMEA3714487_01904)	-	1864627..1864959 (-)	333	WP_001186216.1	phage holin	-
E0F40_RS10040 (SAMEA3714487_01905)	-	1864963..1865262 (-)	300	WP_050203193.1	hypothetical protein	-
E0F40_RS10045 (SAMEA3714487_01906)	-	1865271..1865621 (-)	351	WP_000852245.1	hypothetical protein	-
E0F40_RS10050 (SAMEA3714487_01907)	-	1865624..1865827 (-)	204	WP_001091112.1	hypothetical protein	-
E0F40_RS12520 (SAMEA3714487_01908)	-	1865808..1865924 (-)	117	WP_001063633.1	hypothetical protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=1126371 E0F40_RS10010 WP_000413382.1 1862209..1862511(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=1126371 E0F40_RS10010 WP_000413382.1 1862209..1862511(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4